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Maternal and Pediatric Infectious Disease Branch (MPIDB)

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The MPIDB, formerly the Pediatric, Adolescent, and Maternal AIDS Branch, was formed in 1988 with the mission to support and conduct domestic and international research related to the epidemiology, diagnosis, clinical manifestations, pathogenesis, transmission, treatment, and prevention of HIV infection and its complications in infants, children, adolescents, and women (pregnant and non-pregnant). As the HIV epidemic has evolved in the United States and globally, the MPIDB has ensured that research funded by the Branch reflects these changes and addresses important research opportunities and gaps as they arise. The research gaps in children and pregnant women related to many HIV-associated co-infections, such as tuberculosis, hepatitis, and malaria, have become evident as HIV research has become increasingly global in nature. The MPIDB has responded accordingly by promoting and funding new research related to these infectious pathogens in HIV-infected and -uninfected populations. In addition to HIV and associated infectious diseases, the MPIDB supports and conducts research into the epidemiology, natural history, pathogenesis, transmission, treatment, and prevention of other important infectious diseases, including congenital infections such as cytomegalovirus and toxoplasmosis; tropical diseases specifically affecting children and pregnant women; and vaccine-preventable disease in infants, children, adolescents, and women.


  • Develops and supports domestic and international research and research training programs
  • Develops and supports clinical trials of specific and adjunctive treatment and preventive therapies for HIV and other priority infectious diseases in infants, children, adolescents, and women (including safety and pharmacokinetics of antimicrobial agents in these populations), either independently or in collaboration with other Institutes and agencies
  • Investigates the effect of HIV and other infectious agents and their therapies on pregnant women, pregnancy outcomes, fetuses, and children, and the impact of pregnancy on the course of HIV disease and other infectious diseases
  • Elucidates the impact of therapies used during pregnancy or breastfeeding to treat or prevent infectious diseases on the long-term outcome of exposed infants, children, and adolescents
  • Investigates the gender-specific manifestations of HIV and other infectious diseases and therapies to treat such manifestations
  • Collaborates with other Institutes and agencies to conduct implementation science research that evaluates optimal ways to implement evidence-based prevention and treatment interventions, and assess their effectiveness
  • Develops, supports, and evaluates vaccines, other biomedical modalities, and the full scope of activities for the prevention of HIV infection, HIV-associated infections, and other high-priority infectious diseases in the populations of interest

The Branch collaborates with other NICHD Branches, NIH Institutes, federal agencies such as the Centers for Disease Control and Prevention (CDC), the President's Emergency Plan for AIDS Relief (PEPFAR), and interested private organizations that share a focus on maternal, pediatric, and adolescent HIV infection and related infectious diseases. The Branch's activities target the following goals:

  • Eliminating new pediatric HIV infections in the United States and globally
  • Evaluating new strategies for HIV cure/remission in infants, children, and adolescents
  • Preventing new HIV infections among adolescents, and pregnant and breastfeeding women
  • Optimizing the health of HIV-infected children, adolescents, and women so that they can lead meaningful and productive lives free of the complications of HIV and its treatment
  • Reducing morbidity and mortality due to infectious diseases specifically affecting infants, children, adolescents, and women
Last Reviewed: 02/02/2016

Contact Information

Name: Dr Rohan Hazra
Branch Chief
Maternal and Pediatric Infectious Disease Branch
Phone: 301-435-6868

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