NICHD Contributions to Society

Research conducted and funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has helped save lives, improve wellbeing, and reduce societal costs associated with illness and disability. The following sections provide examples of groundbreaking scientific findings made possible by NICHD.

Citations

  1. U.S. Department of Health and Human Services, National Institutes of Health, Office of Science Policy (n/d). Childhood Hib vaccines: Nearly eliminating the threat of bacterial meningitis. Retrieved January 26, 2022, from https://www.nih.gov/sites/default/files/about-nih/impact/childhood-hib-vaccines-case-study.pdf (PDF 462 KB)
  2. Sontag, M. K., Yusuf, C., Grosse, S. D., Edelman, S., Miller, J. I., McKasson, S., Kellar-Guenther, Y., Gaffney, M., Hinton, C. F., Cuthbert, C., Singh, S., Ojodu, J., & Shapira, S. K. (2020). Infants with congenital disorders identified through newborn screening - United States, 2015-2017. Morbidity and Mortality Weekly Report, 69(36), 1265–1268. PMID: 32915168
  3. Murphy, S. L., Kochanek, K. D., Xu, J. Q., & Arias, E. (2021).  Mortality in the United States, 2020 (NCHS Data Brief, no 427). Hyattsville, MD: National Center for Health Statistics. Retrieved January 26, 2022, from https://www.cdc.gov/nchs/products/databriefs/db427.htm    
  4. Cochrane Library (2022). Cochrane Database of Systemic Reviews, https://www.cochranelibrary.com/cdsr/about-cdsr external link
  5. Morris, B. H., Oh, W., Tyson, J. E., Stevenson, D. K., Phelps, D. L., O'Shea, T. M., McDavid, G. E., Perritt, R. L., Van Meurs, K. P., Vohr, B. R., Grisby, C., Yao, Q., Pedroza, C., Das, A., Poole, W. K., Carlo, W. A., Duara, S., Laptook, A. R., Salhab, W. A., Shankaran, S., … NICHD Neonatal Research Network (2008). Aggressive vs. conservative phototherapy for infants with extremely low birth weight. The New England Journal of Medicine, 359(18), 1885–1896. PMID: 18971491 
  6. Rouse, D. J., Hirtz, D. G., Thom, E., Varner, M. W., Spong, C. Y., Mercer, B. M., Iams, J. D., Wapner, R. J., Sorokin, Y., Alexander, J. M., Harper, M., Thorp, J. M., Jr, Ramin, S. M., Malone, F. D., Carpenter, M., Miodovnik, M., Moawad, A., O'Sullivan, M. J., Peaceman, A. M., Hankins, G. D., … Eunice Kennedy Shriver NICHD Maternal-Fetal Medicine Units Network (2008). A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy. The New England Journal of Medicine, 359(9), 895–905. PMID: 18753646
  7. Trachtenberg, F. L., Haas, E. A., Kinney, H. C., Stanley, C., & Krous, H. F. (2012). Risk factor changes for sudden infant death syndrome after initiation of Back-to-Sleep campaign. Pediatrics, 129(4), 630–638. PMID: 22451703
  8. NIH. (2021). Nobel laureates. The NIH Almanac. Retrieved January 26, 2022, from https://www.nih.gov/about-nih/what-we-do/nih-almanac/nobel-laureates  
  9. Adzick, N. S., Thom, E. A., Spong, C. Y., Brock, J. W., 3rd, Burrows, P. K., Johnson, M. P., Howell, L. J., Farrell, J. A., Dabrowiak, M. E., Sutton, L. N., Gupta, N., Tulipan, N. B., D'Alton, M. E., Farmer, D. L., & MOMS Investigators (2011). A randomized trial of prenatal versus postnatal repair of myelomeningocele. The New England Journal of Medicine, 364(11), 993–1004. PMID: 21306277
  10. NICHD. (2020). Release: Benefits of fetal surgery to repair spina bifida persist through school age, NIH study finds. Retrieved January 26, 2022, from https://www.nichd.nih.gov/newsroom/news/012420-myelomeningocele  
  11. NICHD. (2020). Media advisory: NIH researchers discover gene for rare disease of excess bone tissue growth. Retrieved January 26, 2022, from https://www.nichd.nih.gov/newsroom/news/033120-melorheostosis   
  12. NIH. (2018). Press release: NIH researchers crack mystery behind rare bone disorder. Retrieved January 26, 2022, from https://www.nih.gov/news-events/news-releases/nih-researchers-crack-mystery-behind-rare-bone-disorder
  13. NICHD. Marini Lab: Genetic Disorders of Bone and Extracellular Matrix. 2020 Annual Report of the Division of Intramural Research. Retrieved January 26, 2022, from https://annualreport.nichd.nih.gov/marini.html   
  14. NICHD. (2004). NICHD funded researchers discover gene for Cornelia De Lange syndrome. Retrieved January 26, 2022, from https://www.nichd.nih.gov/newsroom/releases/cornelia    
  15. Tuomala, R. E., Shapiro, D. E., Mofenson, L. M., Bryson, Y., Culnane, M., Hughes, M. D., O'Sullivan, M. J., Scott, G., Stek, A. M., Wara, D., & Bulterys, M. (2002). Antiretroviral therapy during pregnancy and the risk of an adverse outcome. The New England Journal of Medicine, 346(24), 1863–1870. PMID: 12063370
  16. Cooper, E. R., Charurat, M., Mofenson, L., Hanson, I. C., Pitt, J., Diaz, C., Hayani, K., Handelsman, E., Smeriglio, V., Hoff, R., Blattner, W., & Women and Infants' Transmission Study Group (2002). Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. Journal of Acquired Immune Deficiency Syndromes (1999), 29(5), 484–494. PMID: 11981365
  17. N/A. (April 2023). Preventing Perinatal Transmission of HIV. https://www.hiv.gov/hiv-basics/hiv-prevention/reducing-mother-to-child-risk/preventing-mother-to-child-transmission-of-hiv