Publications

Yang S, Ting CY, Lilly MA. (2024). The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs. Mol. Cell. 84:727-743. PMID: 38325378

Wang ZH, Combs C, Zhao W, Zhang F, Knutson J, Lilly MA, Xu H. (2023). Mechanical stimulation from the surrounding tissue activates mitochondrial energy 1 metabolism in differentiating germ cells. Dev. Cell. 58:2249-2260. PMID: 37647895

Zhang, Y., Ting, C-Y., Yang, S., Reich, J., Fru, K., and Lilly, M. A. (2022). Wdr59 promotes or inhibits TORC1 activity depending on cellular context. PNAS. 120, e2212330120. PMCID: PMC9910487.

Zhou, Y., Guo, J., Wang, X., Cheng, Y., Guan, J., Barman, P., Sun, M.A., Fu, Y., Wei, W., Feng, C., Lilly, M.A. and Y. Wei (2021). FKBP39 controls nutrient dependent Nprl3 expression and TORC1 activity in Drosophila. Cell Death Dis 12, 571. 10.1038/s41419-021-03860-z. PMCID: PMC8172852.

Yang S, Zhang Y, Ting CY, Bettedi L, Kim K, Ghaniam E, Lilly MA. (2020) The Rag GTPase regulates the dynamic behavior of TSC downstream of both amino acid and growth factor restriction. Dev. Cell. 2020 PMID: 32898476

Xi J, Cai J, Cheng Y, Fu Y, Wei W, Zhang Z, Zhuang Z, Hao Y, Lilly MA, Wei Y. (2019). The TORC1 inhibitor Nprl2 protects age-related digestive function in Drosophila. Aging. 11, 9811-9828. PMID: 31712450.
Wei Y, Bettedi L, Ting CY, Kim K, Zhang Y, Cai J, Lilly MA. (2019). The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila. eLife. 8:e42149. PMID: 31650955
Rotelli M, Policastro R, Bolling A, Killion A, Weinberg A, Dixon M, Zentner G, Walczak C, Lilly MA, Calvi B. (2019) A Cyclin A-Myb-Aurora B network regulates the choice between mitotic cycles and polyploid endoreplication cycles. PLOS Genetics 15(7):e1008253. PMID: 31291240.

Cai W, Wei Y, Jarnik M, Reich J, Lilly M. 2016. The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function. PLOS Genetics 12(5):e1006036. PMID: 27166823
Wei Y, Reveal B, Cai W, Lilly MA. 2016. The GATOR1 Complex Regulates Metabolic Homeostasis and the Response to Nutrient Stress in Drosophila melanogaster. G3 (Bethesda) 6: 3859-3867. PMID: 27672113

Wei Y, Reveal B, Reich J, Laursen W, Senger S, Akar T, Iida-Jones I, Cai W, Jarnik M, and MA Lilly. (2014) The TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila. PNAS. 111 (52) E5670-E5677. PMID: 25512509
Wei Y and MA Lilly. (2014) The TORC1 inhibitors Nprl2 and Nprl3 mediate anadaptive response to amino acid starvation in Drosophila. Cell Death and Differentiation. 14, 1460-1468. PMID: 24786828

Kassis J and MA Lilly. (2013) PRC2 goes solo in the female germline. Developmental Cell. 26, 329-331. PMID: 23987509

Mitra K, Rikhy R, Lilly M, and J Lippincott-Schwartz. (2012) DRP1-dependent mitochondrial fission inititiates follicle cell differentiation during Drosophila oogenesis. J. Cell Biology. 197, 487-97. PMID: 22584906

Senger S, Csokmay J, Akbar T, Jones TI, Sengupta P, Lilly MA. (2011) The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis. Development. 2011 May;138(10):2133-42. Erratum in: Development. 2011 Jun;138(12):2631. Tanveer, Akbar [corrected to Akbar, Tanveer]. PMID: 21521741

Ullah Z, Lee CY, Lilly MA, DePamphilis ML. (2009) Developmentally programmed endoreduplication in animals. Cell Cycle. 2009 May 15;8(10):1501-9. Epub 2009 May 2. PMID: 19372757
Narbonne-Reveau, K., and M. A. Lilly. (2009) Dacapo promotes genomic stability during premeiotic S phase. Molecular Biology of the Cell. 20: 1960-1969. PMID: 19211840

Narbonne-Reveau K, Senger S, Pal M, Herr A, Richardson HE, Asano M, Deak P, Lilly MA. (2008) APC/CFzr/Cdh1 promotes cell cycle progression during the Drosophila endocycle. Development. 2008 Apr;135(8):1451-61. Epub 2008 Mar 5. PMID: 18321983
Mavrakis, M., Rikhy, R., Lilly, M. A. and J. Lippincott-Schwartz. (2008) Fluorescence imaging techniques for studying Drosophila development. Current Protocols in Cell Biology. Chapter 4. Unit 4.18. PMID: 18551421

Hong A, Narbonne-Reveau K, Riesgo-Escovar J, Fu H, Aladjem MI, Lilly MA. (2007) The cyclin-dependent kinase inhibitor Dacapo promotes replication licensing during Drosophila endocycles. EMBO J. 2007 Apr 18;26(8):2071-82. Epub 2007 Mar 22. PMID: 17380129

Sugimura I, Lilly MA. (2006) Bruno inhibits the expression of mitotic cyclins during the prophase I meiotic arrest of Drosophila oocytes. Dev Cell. 2006 Jan;10(1):127-35. PMID: 16399084

Lilly MA, Duronio RJ. (2005) New insights into cell cycle control from the Drosophila endocycle. Oncogene. 2005 Apr 18;24(17):2765-75. Review. PMID: 15838513
Anderson LK, Royer SM, Page SL, McKim KS, Lai A, Lilly MA, Hawley RS. (2005) Juxtaposition of C(2)M and the transverse filament protein C(3)G within the central region of Drosophila synaptonemal complex. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4482-7. Epub 2005 Mar 14. PMID: 15767569
Morris JZ, Hong A, Lilly MA, Lehmann R. (2005) twin, a CCR4 homolog, regulates cyclin poly(A) tail length to permit Drosophila oogenesis. Development. 2005 Mar;132(6):1165-74. Epub 2005 Feb 9. PMID: 15703281

Snapp EL, Iida T, Frescas D, Lippincott-Schwartz J, Lilly MA. (2004) The fusome mediates intercellular endoplasmic reticulum connectivity in Drosophila ovarian cysts. Mol Biol Cell. 2004 Oct;15(10):4512-21. Epub 2004 Aug 3. PMID: 15292454
Iida T, Lilly MA. (2004) Missing oocyte encodes a highly conserved nuclear protein required for the maintenance of the meiotic cycle and oocyte identity in Drosophila. Development. 2004 Mar;131(5):1029-39. PMID: 14973288
Calvi BR, Lilly MA. (2004) Fluorescent BrdU labeling and nuclear flow sorting of the Drosophila ovary. Methods Mol Biol. 2004;247:203-13. No abstract available. PMID: 14707348

Hong A, Lee-Kong S, Iida T, Sugimura I, Lilly MA. (2003) The p27cip/kip ortholog dacapo maintains the Drosophila oocyte in prophase of meiosis I. Development. 2003 Apr;130(7):1235-42. PMID: 12588841

Lilly MA, de Cuevas M, Spradling AC. (2000) Cyclin A associates with the fusome during germline cyst formation in the Drosophila ovary. Dev Biol. 2000 Feb 1;218(1):53-63. PMID: 10644410

Calvi BR, Lilly MA, Spradling AC. (1998) Cell cycle control of chorion gene amplification. Genes Dev. 1998 Mar 1;12(5):734-44. PMID: 9499407
de Cuevas M, Lilly MA, Spradling AC. (1997) Germline cyst formation in Drosophila. Annu Rev Genet. 1997;31:405-28. Review. PMID: 9442902

Lilly MA, Spradling AC. (1996) The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion. Genes Dev. 1996 Oct 1;10(19):2514-26. PMID: 8843202