Postdoctoral position in structure, biochemistry and chemical biology based understanding of integral membrane enzymes and transition metal transporters

The research group of Dr. Anirban Banerjee at the National Institute of Health (NIH) is seeking candidates for postdoctoral fellows. The broad interests of the lab are in membrane protein structure and function. We are combining structural techniques such as macromolecular crystallography and cryo EM with biophysical and biochemical methods such as reconstitution based functional assays to investigate the structural bases of the mechanisms of integral membrane enzymes and transporters. Recently we have also started projects using cell biology and chemical biology to complement our structural and biochemical studies.

For this position, we are looking for a candidate who will carry out both structural studies and biochemical experiments on integral membrane enzymes that catalyze posttranslational protein lipidation (See Science 12 Jan 2018: Vol. 359, eaao6326; PNAS (2022) 119 (7), e2022050119) and transition metal transporters (see J Biol Chem. 2018 Mar 9;293(10):3819-3828; PNAS (2022) 119 (7), 116 (36), 17775-17785).

The DC Metro area is a wonderful place to live, the weather is pleasant, and the NIH is a vibrant international community. In terms of scientific opportunities, the NIH is absolutely unique in bringing scientists from virtually all areas of biomedical sciences in one campus. Our lab is part of the Cell Biology and Neurobiology Branch in the National Institute of Child Health and Human Development (NICHD). Our lab also has an affiliation to the National Institute of Neurological Disorders and Stroke (NINDS). We interact with several other labs at the NIH who are interested in structural biology and membrane proteins.

Qualifications

The candidates should hold a Ph. D. degree in a related field, be author of at least one first author publication and have a strong background in biochemistry or structural biology. Experience with basic molecular biology, protein expression, purification and biochemical characterization are required. Prior experience in in any one or more of crystallography, cryoEM, membrane protein biochemistry or mammalian expression systems will be added advantages.

It is absolutely essential the candidate is motivated and prepared to put in the best efforts for fruition of the project goals. We are a small, friendly lab and ability to work as part of a cohesive group is important.

Interested candidates can send an email of interest to anirban.banerjee@nih.gov with a CV and a summary of previous research experience and future interests.

The NIH is dedicated to building a diverse community in its training and employment programs.

Postbac position in membrane protein structure and biochemistry

We are always looking for interested postbacs. Past postbacs typically have spent two years in the lab and many have co-authored publications. Experience with basic molecular biology, protein expression, purification and biochemical characterization are added points of advantage. It is essential to have good lab organizational skills and enthusiasm for learning new techniques and following them to detail. Please apply to the NIH postbac program and send an e-mail to anirban.banerjee@nih.gov.

The NIH is dedicated to building a diverse community in its training and employment programs.