Spotlight: Research on Rare Disease of Infancy Provides Insights into Skeletal Disorders
At least 20 babies in the United States are born each year with Generalized Arterial Calcification of Infancy (GACI), a progressive genetic disease. Of those who survive infancy, most develop the skeletal disease rickets. NICHD research seeks to understand the molecular mechanisms underpinning GACI and how they affect skeletal growth and metabolism.