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Uterine Fibroids: Clinical Trials

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The NICHD conducts and supports a variety of clinical research related to uterine fibroids. Select a link below to learn more about these projects.

Featured NICHD Clinical Trials

  • The FIRSTT: Comparing MRgFUS (MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization) for Uterine Fibroids
    This study is comparing the safety and effectiveness of two standard fibroid treatments: MRI-guided ultrasound surgery (MRgFUS) and uterine artery embolization (UAE). It will also collect information to understand which symptoms bother women with fibroids the most.
  • NIH Fibroid Treatment Study
    This study is evaluating a new medical treatment for fibroids using a drug that changes how the body responds to the hormone progesterone. The study will compare fibroid size, hormone levels, and symptoms before and during daily administration of the medication or a placebo (a treatment that looks like the real thing, but contains no medication) for 10 to 14 weeks. Women will have a hysterectomy at the end of the study to provide a cure and to evaluate the effects of the medication on the uterine and fibroid tissues.
  • Fibroid Tissue Bank
    The purpose of this study is to collect information and tissue samples from women who have uterine fibroids. The samples, collected during surgery, will be used to study genes, proteins, and other aspects of fibroids to better understand how they develop and grow, and to help improve fertility and reproductive health.

NICHD Clinical Trials

ClinicalTrials.gov Search Results

Information on current NIH-sponsored clinical trials is available by following the link below or by calling 1-800-411-1222.

Last Updated Date: 01/21/2014
Last Reviewed Date: 12/18/2013
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology