The Human Placenta Project: Placental Structure and Function in Real Time

Human Placenta Project logo

May 27–28, 2014

Sponsor/Co-Sponsor(s)

NICHD

Agenda


May 27, 2014

7:30 a.m.Goals for Human Placenta Project (HPP) and Workshop 
Alan Guttmacher and Cathy Spong
 
  
  
7:40 a.m.Introductions
Alan Guttmacher and Cathy Spong
  
  
8:00 a.m.Overview of Placental Formation and Structure (PDF - 3.2 MB)
Graham Burton
 
  
  
8:45 a.m.Maternal Placental Syndromes: Conditions Due to Placental Abnormalities (PDF - 1.9 MB)
George Saade
 
  
  
9:30 a.m.Current Methods for Assessing Placental Development and Function and Their Limitations (PDF - 3 MB)
Yoel Sadovsky
 
  
  
10:15 a.m.Break
  
  
10:30 a.m.

Panel Discussion: Shared Pathophysiological Processes That May Be Assessed Using Knowledge and Technologies From Other Fields 
(6-Minute Presentations on the Specific Dysfunction and Its Relevance, Followed by Discussion)

  
  
11:15 a.m.Lunch
  
  
12:00 p.m.

Breakout Sessions: Shared Pathophysiological Processes that may be Assessed Using Knowledge and Technologies from Other Fields

  • Breakout 1: Anatomy and Tissue Structure: Led by Susan Fisher
  • Breakout 2: Utero-Placental Perfusion: Led by Kathleen Schmainda
     
  • Breakout 3: Tissue and Cellular Metabolism (e.g., Nutrient Transfer, Biochemistry, -omics): Led by Nick Illsley
  • Breakout 4: Immunology, Inflammation (e.g., Graft vs. Host Interactions): Led by Gil Mor

Charge to Breakout Sessions:

  • What functions are important to evaluate in real time?
  • What are the current state-of-the-art approaches in obstetrics for assessing these processes?
  • How are these processes assessed in other fields?
  • What technologies might be applicable to HPP?
  • What technologies need to be developed to address the pathophysiologic process?
  
  
2:00 p.m.Breakout Groups Report Back, Followed by Discussion
  
  
3:30 p.m.

Panel Presentation: Applying Technologies To Study the Placenta in Real Time: Currently Utilized Imaging Technologies—How To Optimize or Further Their Use
(6-Minute Presentations, Followed by Discussion)

  
  
4:00-6:00 p.m.

Breakout Sessions: Currently Utilized Imaging Technologies—How To Optimize or Further Their Use

  • Breakout 1: Ultrasound: Led by Alfred Abuhamad
     
  • Breakout 2: MRI: Led by John Sled
     

Charge to Breakout Groups:

  • What are the "adjacent possible" to application in obstetrics for each technology?
  • What technologies might be applicable to HPP?
  • What technologies need to be developed to address the pathophysiologic process?
  • Describe what needs to be done to develop/stimulate/
    encourage/facilitate this area to move forward to understand human placental structure and function in real time.
  • Are there initial steps that must first occur (e.g., technologies to develop)?
  
  
6:00 p.m.Adjourn



 

 

May 28, 2014

  
8:00 a.m.Breakout Groups Report Back: Currently Utilized Imaging Technologies—How To Optimize or Further Their Use
  
  
9:00 a.m.

Panel Presentation: Emerging or Potentially Promising Technologies—How To Develop and/or Optimize Their Use 
(6-Minute Presentations on the Technology, Followed by Discussion)

  
  
10:15 a.m.

Breakout Sessions: Emerging or Potentially Promising Technologies—How To Develop and/or Optimize Their Use

  • Breakout 1: Nanotechnology (e.g., Nanorobots, Intravascular Sensors): Led by Erik Rytting
  • Breakout 2: Biochemical Techniques: Led by Carolyn Ott
     
  • Breakout 3: High-Throughput –omics: Led by Diana Bianchi
     
  • Breakout 4: Systems Science, Computational Biology: Led by Brian Cox
     
  • Breakout 5: Data Management (e.g., Sharing, Manipulation, Reconstruction): Led by Peter Basser
     

Charge to Breakout Groups:

  • What are the "adjacent possible" to application in obstetrics for each technology?
  • What technologies might be applicable to HPP?
  • What technologies need to be developed to address the pathophysiologic process?
  • Describe what needs to be done to develop/stimulate/ encourage/facilitate this area to move forward to understand human placental structure and function in real time.
  • Are there initial steps that must first occur (e.g., technologies to develop)?
  
  
12:30 p.m.Lunch
  
  
  
1:30 p.m.Breakout Groups Report Back, Identifying More Specific 
Targets for HPP Phase I
  
  
3:15 p.m.Design and Develop the HPP "Roadmap"
Alan Guttmacher and Cathy Spong
  
  
4:15 p.m.Wrap Up and Next Steps
Alan Guttmacher
  
  
4:30 p.m.Adjourn



 

 

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