Development of a method of isolating single vertebrate nerve fibers and of measuring electrical properties of the myelin sheath and node of Ranvier (demonstration of saltatory conduction in the myelinated nerve fiber) Am. J. Physiol., 125, 380 (1939); 127, 211, (1939); Pflueger's Arch. f. d. ges. Physiol. 244, 696 (1941), 245, 764 (1942).
Demonstration of traveling waves in the guinea pig cochlea by recording cochlear microphonics. J. Acous. Soc. Am. 24, 502 (1952).
Recording of afferent impulses from individual primary auditory nerve fibers. J. Neurophysiol. 17, 97 (1954).
Invention of the double-cannulation method of internal perfusion of the squid giant axon and analyses of the bi-ionic action potential. Acta Physiol. Scand. 52, 195 (1961); Proc. Nat. Acad. Sci. 58, 2246 (1967). Physiology and Electrochemistry of Nerve Fibers. Academic Press, New York (1982).
Demonstration and analyses of extrinsic fluorescence signals associated with nerve excitation and conduction. Proc. Nat. Acad. Sci. 61, 883 (1968); Photochem. Photobiol. 24, 191 (1976).
Development of the polyvinylidine fluoride (PVDF) method of detecting rapid heat production in nervous tissues. Biochem. Biophys. Res. Commun. 101, 172, (1981); Biophys. J. 55, 1033 (1989).
Demonstration of physical-chemical changes and analyses of rapid swelling in nerve fibers, cells and synapses associated with excitation processes. Biochem. Biophys. Res. Commun. 95, 1328 (1980); Ferroelectrics 220, 309 (1999).
Demonstration and analyses of macromolecular phase-transitions associated with Ca2+-Na+ exchange in biopolymers and nervous tissues. Biopolymers 32, 1019 (1992); Jpn. J. Physiol. 49, 297 (1999); J. Theor. Biol (2002).
Bibliography of Ichiji Tasaki
Kot, G., Kaku, Z., and Tasaki, I. On the reflex excitation and inhibition by a single nerve fiber in warm-blooded animals. In: Problems in Nervous Physiology and of Behavior. Tbilisi, 1936, (pp. 203-207).
Tasaki, I. Microphysiologische Untersuchung über die Grundlage der Erregungsleitung in der markhaltigen Nervenfaser. Pflügers Arch ges Physiol 244: 125-141, 1940.
Tasaki, I. Das Schwellenabsinken bei Reizung einer Nervenfaser mit kurzen Stromstössen. Pflügers Arch ges Physiol 245: 665-679, 1942.
Takeuchi, T. and Tasaki, I. Übertragung des Nervenimpulses in der polarisierten Nervenfaser. Pflügers Arch ges Physiol 246: 33-43, 1942.
Tasaki, I. On the slow, small motor nerve fibers in the frog. (In Japanese) Jokenhansha 5: 1-7, 1942.
Tasaki, I., Yuasa, K., and Morii, I. On the mechanism of suspension of nervous transmission by narcosis. Jpn J Med Sci III, Biophysics, 9: 183-188, 1943.
Tasaki, I. and Mizutani, K. Comparative studies on the activities of the muscle evoked by two kinds of motor nerve fibers. Part I. Myographic studies. Jpn J Med Sci III, Biophysics, 10: 237-244, 1944.
Tasaki, I. and Tsukagoshi, M. Comparative studies on the activities of the muscle evoked by two kinds of motor nerve fibers. Part II, the Electro-myogram. Jpn J Med Sci III, Biophysics, 10: 245-251, 1944.
Tasaki, I. Physiology of the Nerve Fiber. Kawai Publishing Co., Tokyo, 1944.
Tasaki, I. The strength-duration relation in photic stimulation of the dark-adapted human eye. Igaku-to-Seibutsugaki, 5: 506-509, 1944.
Tasaki, I. Modification of the rhythm of the heart-beat by a subthreshold low-frequency A. C. Igaku-to-Seibutsugaku, 5: Vol. II, 311-316, 1947.
Tasaki, I. and Mizuguchi, K. The changes in the electric impedance during activity and the effect of alkaloids and polarization upon the bioelectric processes in the myelinated nerve fiber. Biochem Biophys Acta, 3: 484-493, 1949.
Tasaki, I. Collision of two nerve impulses in the nerve fiber. Biochem Biophys Acta, 3: 494-497, 1949.
Tasaki, I. The excitatory and recovery processes in the nerve fiber as modified by temperature changes. Biochem Biophys Acta, 3: 498-509, 1949.
Tasaki, I. and Tasaki, N. The electrical field which a transmitting nerve fiber produces in the fluid medium. Biochem Biophys Acta, 5: 335-342, 1950.
Tasaki, I. Excitation of single nerve fiber by action current from another single fiber. J Neurophysiol 13: 177-183, 1950.
Tasaki, I. Electrical excitation of the nerve fiber. Part 1. Excitation by linearly increasing currents. Jpn J Physiol 1: 1-6, 1950.
Tasaki, I. and Sakaguchi, M. Electrical excitation of the nerve fiber. Part II. Excitation of exponentially increasing currents. Jpn J Physiol 1: 7-15, 1950.
Tasaki, I. Nature of the local excitatory state in the nerve fiber. Jpn J Physiol 1: 75-85, 1950.
Tasaki, I. The threshold conditions in electrical excitation of the nerve fiber. Parts 1 and 2. Cytologia, 3-4: 205-236, 1950.
Tasaki, I. and Kamiya, N. Electrical response of a slime mold to mechanical and electrical stimuli. Protoplasma, 39: 333-343, 1950.
Hodler, J. Stämpli, R., and Tasaki, I. Die Wirkung von Veratrin auf die einzelne markhaltige Nervenfaser. Helv Physiol Acta, 8: C62-C63, 1950.
Tasaki, I. and Ushiyama, J. Über den Effekt von Saponin und einigen anderen Chemikalien auf die Erregungsleitung der einzelnen markhaltigen Nervenfaser. Helv Physiol Acta, 8: C77-C79, 1950.
Tasaki, I. and Ushiyama, J. The effect of saponine and several other chemicals upon the action current led through the myelin sheath. Arch Internaz Stud Neurol 1: (Fasc. 2) 1-6, 1950.
Sato, M. and Tasaki, I. Afferent impulses in the depressor nerve. Jpn J Physiol 1: 173-178, 1951.
Tasaki, I. and Fernandez, C. Effect of direct current upon the cochlear microphonic and action potential of the guinea pig. Amer J Physiol 3: 167, 1951.
Hodler, J., Stämpli, R., and Tasaki, I. Über die Wirkung internodaler AbKühlung auf die Errgegungsleitung in der isolierten markhaltigen Nervenfaser des Frosches. Pflügers Arch ges Physiol 253: 380-385, 1951.
Hodler, J., Stämpli, R., and Tasaki, I. Änderung der Reizschwelle und der Chronaxie langs einer einzelnen markhaltigen Nervenfaser. Helv Physiol Acta, 10: C54-C55, 1952.
Tasaki, I. Properties of myelinated fibers in frog sciatic nerve and in spinal cord as examined with microelectrodes. Jpn J Physiol 3: 73-94, 1952.
Tasaki, I. Conduction of impulses in the myelinated nerve fiber. Cold Spring Harbor Symp. Quant. Biol 17: 37-41, 1952.
Davis, H., Tasaki, I., and Goldstein, R. The peripheral origin of activity with reference to the ear. Cold Spring Harbor Symp. Quant. Biol 17: 143-154, 1952.
Freygang, Jr., W.H., Spyropoulos, C.S., and Tasaki, I. Simultaneous measurements of membrane impedance and voltage. Am J Physiol 183: 617, 1955. ABSTRACT (Presented at the Am Phys Soc, Medford, Mass.)
Tasaki, I. Hearing. In: Ann Rev Physiol 19: 417-438, 1957.
Tasaki, I. and Spyropoulos, C.S. Influence of changes in temperature and pressure on the nerve fiber. In: The Influence of Temperature on Biological Systems. F. S. Johnson (Ed.), Waverly Press, Baltimore, p. 201-220, 1957.
Tasaki, I. and Bak, A. Oscillatory membrane currents of the squid giant axon under voltage-clamp. Sci 126: 696-697, 1957.
Tasaki, I. Studies on the process of production of an action potential at a single node of Ranvier. In: Microphysiologie Comparée des Éléments Excitables. (67ième Colloques Intemationaux) Paris, Centre National de la Recherche Scientifique, p. 27, 1955.
Spyropoulos, C.S., Tasaki, I., and Brady, R. The effects of oxidizing agents under the electrophysiological properties of the nerve fiber. Section 14: 181, 1958 (Presented at the Intl. Biochemical Conf., Vienna, Austria.) ABSTRACT
Hild, W., Chang, J.J. and Tasaki, I. Electrical responses of astrocytic glia from the mammalian central nervous system cultivated in vitro. Experientia, Basle 14: 220-221, 1958.
Hagiwara, S. and Tasaki, I. A study on the mechanism of impulse transmission across the giant synapse of the squid. J Physiol, London 143: 114-137, 1958.
Tasaki, I. and Chang, J.J. Electric response to glia cells in cat brain. Sci 128: 1209-1210, 1958.
Tasaki, I. Conduction of nerve impulse. Chapter III, In: Handbook of Physiology, Section 1: Neurophysiology, Vol 1, J. Field, H.W. Magoun and V.E. Hall (Eds.), Am Physiol Soc, p. 75-121, 1958.
Tasaki, I. Physiological properties of the myelin sheath and of the node of Ranvier. In: The Biology of Myelin, Vol. IV, Progress in Neurobiology, S.R. Korey (Ed.) New York, Hoeber-Harper, p. 159-172, 1959.
Tasaki, I. Afferent impulses in auditory nerve fibers and the mechanism of impulse initiation in the cochlea. In: Neuronal Mechanisms of the Auditory and Vestibular Systems. G.L. Rasmussen and W.F. Windle (Eds.), Springfield, Charles C. Thomas, p. 40-47, 1962.
Tasaki, I. Nervous activity in abnormal fluid media. In: Neural Physiopathology, Progress in Neurobiology, Vol. 8, R.S. Grenell (Ed.), Harper & Row Publishers, p. 266-288, 1962.
Tasaki, I. Ionic transport across neural and non-neural membranes. Discussion at symposium. In: Properties of Membranes and Diseases of the Nervous System, New York, Springer Publishing Co., p. 100-102, 1962.
Tasaki, I., Watanabe, A., and Takenaka, T. Resting and action potential of intracellularly perfused squid giant axons. Proc Natl Aca Sci 48: 1177-1184, 1962.
Tasaki, I. Movement of radio-isotopes across squid membrane at rest and during activity. (Presented at symposium on Biophysics of Peripheral Nerves, XXII International Congress of Physiological Sciences, Leiden, The Netherlands, 1962).
Tasaki, I. and Shimamura, M. Further observations on resting and action potential of intracellularly perfused squid axon. Proc Natl Aca Sci 48: 1571-1577, 1962.
Tasaki, I. and Takenaka, T. Resting and action potential of squid giant axons intracellularly perfused with sodium-rich solutions. Proc Natl Aca Sci 50: 619-626, 1963.
Tasaki, I. and Takenaka, T. Ion fluxes and excitability in squid giant axon. In: The Cellular Functions of Membrane Transport. J.F. Hoffman (Ed.) Englewood Cliffs, NJ, Prentice-Hall, p. 95-111, 1964.
Tasaki, I. and Kamiya, N. A study on 212 properties of carnivorous amoebae. J Cell Comp Physiol 63: 365-380, 1964.
Tasaki, I. Excitability of neurons and glial cells. In: Progress in Brain Research, Vol. 15, Biology of Neuroglia, E.D.P. De Robertis and R. Carrea (Eds.), Amsterdam, Elsevier Publishing Co., p. 234-242. 1965.
Singer, I. and Tasaki, I. Excitability of intracellularly perfused squid giant axon and physico-chemical effects of salts on membrane macromolecules. Fed Proc 24: 1965. ABSTRACT
Tasaki, I. and Singer. I. Electrical excitability of vertebrate and invertebrate nerve fibers. (Presented at symposium on Comparative Neurophysiol. Tokyo, Japan, 1965). ABSTRACT
Tasaki, I. and Singer, I. A macromolecular approach to the excitable membrane. J Cell Comp Physiol 66: 137-146, 1965.
Watanabe, A., Tasaki, I., and Lerman, L. A study of the effects of divalent cations on squid giant axons. Biol Bull 131: 411, 1966. ABSTRACT.
Tasaki, I. and Singer, I. Membrane macromolecules and nerve excitability: A physico-chemical interpretation of excitation in squid giant axons. Ann NY Acad Sci 137: 792-806, 1966.
Watanabe, A., Tasaki, I., and Lerman, L. Bi-ionic action potentials in squid giant axons intracellularly perfused with sodium salts. Biol Bull 133: 491, 1967.
Lerman, L., Watanabe, A. and Tasaki, I. Intracellular perfusion of squid giant axons: Recent findings and interpretations. In: Neuroscience Research, Vol. 2, S. Ehrenpreis and O. Solnitzky (Eds.), Academic Press, 1969.
Tasaki, I., Barry, W., and Carnay, L. Optical and electrophysiological evidence for conformational changes in membrane macromolecules during nerve excitation. In: Physical Principles of Biological Membranes. F. Snell, J. Wolken, G. J. Iverson and J. Lam (Eds.) Gordon & Breach Science Publishers, New York, p. 17-34, 1970.
Tasaki, I. Effects of ultraviolet and visible light on nerve fibers and changes in optical properties during nervous activity. In: Advances in Biological and Medical Physics, Vol. 13, J. H. Lawrence and J. W. Gofman (Eds.), Academic Press, New York, p. 307-327, 1970.
Watanabe, A., Tasaki, I., and Hallett, M. Fluorescence analysis of the excitation process in nerve using hydrophobic probes. Biol Bull 139: 441-442, 1970. ABSTRACT
Tasaki, I. Fluorescence changes in dye-treated nerve following electric stimulation. (PDF 358 KB) In: Probes of Structure and Function of Macromolecules and Membranes. Vol. 1, Probes and Membrane Function. B. Chance, C-P. Lee and J.K. Blasie (Eds.) Academic Press, New York, pp. 235-237, 1971.
Carnay, L. D. and Tasaki, I. Ion exchange properties and excitability of the squid giant axon. Biophysics and Physiology of Excitable Membranes. W. J. Adelman, Jr. (Ed.), Van Nostrand Reinhold Co., New York, p. 379-422, 1971.
Kobatake, Y., Tasaki, I., and Watanabe, A. The bi-ionic action potential and indispensability of divalent cations in the external medium for nerve excitation. In: Cellular Mechanisms for Calcium Transfer and Homeostasis. G. Nichols, Jr. and R. H. Wassennan (Eds.), Academic Press, New York, p. 77-100, 1971.
Tasaki, I. Nerve excitation and "phase transition" in membrane macromolecules. In: Biogenic Amine and Physiological in Drug Therapy. J. H. Biel and L.G. Abood (Eds.), Academic Press, New York, p. 73-105, 1971.
Tasaki, I., Schneider, A., and Carbone, E. Studies of the excitation process in nerve with extrinsic fluorescence. Biol Bull 141: 388-389, 1971. ABSTRACT
Watanabe, A. and Tasaki, I. Intracellular perfusion of squid giant axons: A study of bi-ionic action potentials. In: Perspectives in Membrane Biophysics. D. Agin (Ed.), Gordon and Breach, New York, p. 65-99, 1972.
Tasaki, I., Sisco, K., and Warashina, A. Difference in fluorescence behavior positional isomers of aminoaphthalene derivations applied internally to squid giant axons. Biol Bull 145: 457, 1973. ABSTRACT.
Tasaki, I., Carbone, E., Sisco, K., and Singer, I. Spectral analyses of extrinsic fluorescence of the nerve membrane labelled with aminonaphthalene derivatives. Biochim Biophys Acta 323: 220-233, 1973.
Tasaki, I., Warashina, A., and Pant, H. Energy transfer between fluorescent probe molecules in and across nerve membrane. Biol Bull 147: 501, 1974. ABSTRACT
Tasaki, I. Evidence for phase-transition in nerve membrane. In: Progress in the Neurosciences and Related Fields. S. L. Mintz and S. M. Widmayer, (Eds.), Plenum Publishing Corp., New York, p. 56-66, 1974.
Tasaki, I. Nerve Excitation. New experimental evidence for the macromolecular hypothesis. In: Trends in Neurophysiology. Monnier (Ed.), Masson et Cie, France, p. 79-90, 1974.
Tasaki, I. and Carbone, E. A macromolecular approach to nerve excitation. In: Current Topics in Membranes and Transport, Vol. 5, F. Bronner and A. Kleinzeller (Eds.), Academic Press, New York, p. 283-325, 1974.
Tasaki, I. and Sisco, K. Electrophysiological and optical methods for studying the excitability of the nerve membrane. In: Methods in Membrane Biology, Vol. 5, E. D. Korn (Ed.), Plenum Press, New York, p. 163-193, 1975.
Tasaki, I. and Warashina, A. Changes in light absorption, emission and energy transfer produced by electric stimulation of nerves labeled with fluorescent probes. Proc. J Acad. 51: 604-609, 1975.
Tasaki, I. Evolution of theories of nerve excitation. In: The Nervous System, Vol. 1, The Basic Neurosciences, D. B. Tower (Ed.), Raven Press, New York, p. 177-195, 1975.
Tasaki, I. Chronaxie and transitional decrement: A review of Dr. Davis' contributions to Physiology of Nerve Fibers. Washington University Press, St. Louis, Missouri, p. 1-10, 1976.
Inoue, I., Pant, H. C., Tasaki, I., and Gainer, H. Release of proteins from the inner surface of squid axon membrane labeled with tritiated N-Ethylmaleirnide. J Gen Physiol, Vol. 68, p. 385-395, 1976.
Tasaki, I. Physico-chemical properties of the nerve membrane. In: Charged Gels and Membranes, Vol. 4, E. Sélégny (Ed.), D. Reidel Publ. Co, Dordrecht-Holland, p. 213-238, 1976.
Matsumoto, G., Tasaki, I., and Inoue, I. Oscillatory subthreshold responses and potential fluctuation observed in squid giant axons. J Phys Soc Japan 44: 351-352, 1978.
Tasaki, I. and Matsumoto, G. Optical probes of axonal membrane. In: Physiology and Pathobiology of Axons, S. G. Waxman (Ed.), Raven Press, New York, p. 237-250, 1978.
Baumgold, J., Matsumoto, G., and Tasaki, I. Biochemical studies of nerve excitability: The use of protein modifying reagents for characterizing sites involved in nerve excitation. J Neurochem 30: 91-100, 1978.
Tasaki, I. Chemical stimulants and real-time spectrum analyzer used for studying properties of membrane excitable sites. In: Abnormal Neuronal Discharges. N. Chalazonitis and M. Boisson (Eds.), Raven Press, New York, p. 233-242, 1978.
Metuzals, J., Terakawa, S., and Tasaki, I. The axolemma-ectoplasm complex investigated in desheathed squid giant axons. In: Electron Microscopy, Vol. 2, p. 12-13, 1980. Presented at the Proc. of the 7th Euro Cong on Electron Microscopy, The Hague, The Netherlands.
Tasaki, I. and Iwasa, K. Swelling of nerve fibers during action potentials. Upsala J Med Sci 85: 211-215, 1980.
Tasaki, I. Optical changes during electrogenesis. In: Physiology of Excitable Membranes, Vol. 4, J Salánk (Ed.), Adv Physiol Sci, p. 163-170, 1980. Presented at the 28th Internatl Cong of Physiol Sci, Budapest.
Tasaki, I. and Iwasa, K. Swelling of squid giant axon during action potentials. Biol Bull 159: ABSTRACT
Tasaki, I. and Iwasa, K. Rapid mechanical changes in crab nerve and squid axon during action potentials. J Physiol (Paris) 77: 1055-1059, 1981.
Tasaki, I. and Iwasa, K. A physicochemical approach to calcium-membrane macromolecule interactions. In: Mechanism of Gated Calcium Transport Across Biological Membranes. S. T. Ohniski and M. Endo (Eds.), Academic Press, p. 183-189, 1981.
Iwasa, K. and Tasaki, I. Rapid pressure changes of the squid axon accompanied by prolonged action potentials. Biol Bull 161: 346, 1981. ABSTRACT
Tasaki, I. and Terakawa, S. Oscillatory miniature responses in the squid giant axon: Origin of rhythmical activities in the nerve membrane. In: Cellular Pacemaker, Mechanisms of Pacemaker Generation, Vol. 2, D. Carpenter (Ed.), John Wiley and Sons, Inc., p. 163-186, 1982.
Iwasa, K. and Tasaki, I. Swelling of axon membrane during excitation. In: Membrane and Transport, Vol. 2, A. Martonosi (Ed.), Plenum Publishing Co., p. 385-388, 1982.
Pant, H., Terakawa, S., Baumgold, J., and Tasaki, I. Protein release from the internal surface of the squid giant axon membrane during excitation and during application of agents which modify excitation. In: Biomolecular Structure, Conformation, Function and Evolution, Vol. 2, R. Srinivasan, N., Yathindra and E. Subramanian (Eds.), Pergamon Press, p. 513-522, 1982.
Tasaki, I. Origin of periodicity in axon membrane. In: Physiology and Pharmacology of Epileptogenic Phenomena. M. R. Klee, H. D. Lux and E. J. Speckmann (Eds.), Raven Press, p. 335-342, 1982.
Tasaki, I. Measurements of rapid mechanical changes in nerve fibers. (Presented at the 35th Ann. Conf On Engvr. in Med. and Biol., Phila., PA, 22-24 Sept. 1982) ABSTRACT
Metuzals, J., Clapin, D. F., and Tasaki, I. The axolemma-ectoplasm complex of squid giant axon. In: Structure and Function in Excitable Cells. Chang, D., Tasaki, I., Adelman, W., and Leuchtag, R. (Eds.), Plenum Publishing Corp., p. 53-73, 1983.
Tasaki, I. and Iwasa, K. Axolemma-ectoplasm complex and mechanical responses of the axon membrane. In: Structure and Function in Excitable Cells. Chang, D., Tasaki, I., Adelman, W., and Leuchtag, R. (Eds.), Plenum Publishing Corp., p. 307-319, 1983.
Tasaki, I., Nakaye, T., and Byrne, P.M. Swelling of axon membrane during excitation. (Presented at the XXIX International Union of Physiological Sciences) Adelaid, So. Australia and Sydney, Australia, 8/26 - 9/3/83.
Tasaki, I. and Nakaye, T. Rapid mechanical changes in the nervous system during excitation. (Presented at the Seiriken Conference, Okazaki, Japan, Dec. 1983), 1984.
Tasaki, I. On the mechanism of hypersensitivity of nerve fibers and cells. In Inactivation of Hypersensitive Neurons. N. Chalazonitis (ed.), Alan R. Liss, Inc., 1987, p. 311-319.
Tasaki, I. Excitation process and swelling of nerve fibers. In "Polymer Gels: Fundamentals and Biomedical Applications". D. DeRossi et al. (Eds). Plenum Press, New York, 93-110, 1991.
Horkay, F., Tasaki, I., and Basser, P.J. Thermodynamic properties of polyacrylate networks swollen in physiological salt solutions. Abstr Pap Am Chem S. 219: 355-BIOT Part 1, Mar 26, 2000.
Horkay, F., Tasaki, I., and Basser, P.J. Volume transition of polyacrylate hydrogels induced by monovalent-divalent cation exchange in physiological salt solutions. Abstr Pap Am Chem S. 220: 256-PMSE Part 2, Aug 20, 2000.
Horkay, F., Haselkorn, K., Tasaki, I., and Basser, P.J. Swelling kinetics of polyacrylate gel beads in physiological salt solutions. Abstr Pap Am Chem S. 223(2): 105-POLY, April 2002.