Table 8. Adult Test Scores for PKUCS Subjects Grouped by Usual Adult Phe Level (Values tabulated are mean ± s.d.)
* Change from 12-year WISC-R or WRAT score
** p-values are for illustration only, due to small sample sizes
- WAIS-R - | - WRAT 3 - | |||||||
---|---|---|---|---|---|---|---|---|
n | Verbal | Perform | Full | n | Reading | Spelling | Arithmetic | |
Usual Adult Phe Level < 15.9 mg/dl | ||||||||
Parent IQ | 11 | 117±8 | ||||||
Adult Score | 11 | 106±11 | 111±13 | 109±12 | 10 | 108±5 | 107±6 | 103±6 |
Change* | 11 | +5 | +6 | +6 | 8 | 0 | +5 | +16 |
p** | 0.28 | 0.08 | 0.12 | 0.96 | 0.23 | 0.0009 | ||
Usual Adult Phe Level 16.0 - 19.9 mg/dl | ||||||||
Parent IQ | 17 | 104±8 | ||||||
Adult Score | 17 | 94±11 | 99±14 | 96±13 | 14 | 98±9 | 100±9 | 95±13 |
Change* | 14 | +1 | +3 | +2 | 11 | +2 | +3 | +10 |
p** | 0.57 | 0.21 | 0.39 | 0.37 | 0.26 | 0.01 | ||
Usual Adult Phe Level 20.0 - 23.9 mg/dl | ||||||||
Parent IQ | 10 | 110±11 | ||||||
Adult Score | 11 | 95±16 | 94±16 | 94±16 | 10 | 96±12 | 99±16 | 92±11 |
Change* | 9 | +4 | +2 | +3 | 8 | -4 | +4 | +11 |
p** | 0.13 | 0.64 | 0.28 | 0.25 | 0.38 | 0.001 | ||
Usual Adult Phe Level 24.0 - 27.9 mg/dl | ||||||||
Parent IQ | 12 | 103±14 | ||||||
Adult Score | 13 | 88±13 | 92±12 | 88±12 | 11 | 88±21 | 87±21 | 89±24 |
Change* | 11 | -3 | -6 | -6 | 8 | -4 | +2 | +12 |
p** | 0.19 | 0.09 | 0.07 | 0.17 | 0.48 | 0.005 | ||
Usual Adult Phe Level => 28.0 mg/dl | ||||||||
Parent IQ | 12 | 106±11 | ||||||
Adult Score | 12 | 90±11 | 94±17 | 90±14 | 12 | 97±17 | 94±16 | 88±15 |
Change* | 8 | -2 | -2 | -3 | 9 | 0 | -1 | +6 |
p** | 0.35 | 0.58 | 0.22 | 0.90 | 0.76 | 0.11 |