Table 2. History and Blood Phe Levels of 67 PKUCS Subjects Enrolled in the Adult Follow-up Study(Values tabulated are mean ± s.d.)
Age (years) Diet Discontinued | n | Max Dx Phe (mg/dL) | Age 1st Tr. (days) | 6 years Blood Phe Level (mg/dL) | 10 years Blood Phe Level (mg/dL) | Current Blood Phe Level (mg/dL) |
---|---|---|---|---|---|---|
4.8 - 6.5 years | 36 | 49±12 | 21±11 | 13±4 | 27±6 | 24±7 |
4.8 - 6.5 years Never Resumed | 22 | 49±12 | 23±12 | 14±4 | 27±6 | 27±6 |
4.8 - 6.5 years Some Additional Treatment | 14 | 49±9 | 19±10 | 13±4 | 26±6 | 20±7 |
6.5 - 12.5 years | 13 | 57±15 | 21±16 | 12±5 | 20±6 | 26±10 |
6.5 - 12.5 years Never Resumed | 7 | 58±14 | 28±19 | 14±5 | 21±8 | 26±7 |
6.5 - 12.5 years Some Additional Treatment | 6 | 57±17 | 13±5 | 9±3 | 19±5 | 25±13 |
12.5 - 20.0 years | 11 | 48±9 | 19±9 | 12±5 | 14±5 | 20±7 |
12.5 - 20.0 years Never Resumed | 5 | 48±2 | 19±9 | 12±5 | 15±53 | 23±5 |
12.5 - 20.0 years Some Additional Treatment | 6 | 48±13 | 19±9 | 11±7 | 14±7 | 18±8 |
Never Discontinued | 7 | 41±10 | 16±13 | 9±3 | 11±3 | 16±6 |