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Preeclampsia is a syndrome that occurs during pregnancy and is marked by a sudden increase in the blood pressure of a pregnant woman after the 20th week of pregnancy. It can affect the mother's kidneys, liver, and brain. The condition can be fatal for the mother and/or the baby and can lead to long-term health problems.

​Preterm births have fallen for the fifth straight year in a row, reported the National Center for Health Statistics of the Center for Disease Control and Prevention, in one of its recent National Vital Statistics Reports. This welcome decline was seen for all groups, and for each stage of pregnancy.

Item of Interest: Video Presentation: Role of Research in Understanding, Preventing, and Treating Birth Defects

Prenatal steroids--given to pregnant women at risk for giving birth prematurely--appear to improve survival and limit brain injury among infants born as early as the 23rd week of pregnancy, according to a study by a National Institutes of Health research network.

An NIH scientist whose landmark collaborations led to a major advance in understanding a potentially fatal disorder of pregnancy has passed away.

An inexpensive instructional program to teach routine newborn care skills to midwives in Zambia resulted in a substantial reduction in the death rate of infants in the first week of life, according to a study funded by the National Institutes of Health and the Bill and Melinda Gates Foundation.

A National Institutes of Health study has found that progesterone, a naturally occurring hormone, reduced the rate of preterm birth before the 33rd week of pregnancy by 45 percent among one category of at risk women.

Recently, scientists in an NIH study reported that a surgical procedure to repair a common birth defect of the spine, if undertaken while a baby is still in the uterus, greatly reduces the need to divert, or shunt, fluid away from the brain, according to a study by the National Institutes of Health and four research institutions. The fetal surgical procedure also increases the chances that a child will be able to walk without crutches or other devices.

A surgical procedure to repair a common birth defect of the spine, if undertaken while a baby is still in the uterus, greatly reduces the need to divert, or shunt, fluid away from the brain, according to a study by the National Institutes of Health and four research institutions.

Myelomeningocele (MY-ell-oh-men-NING-guh-seal) is the most severe form of spina bifida, a birth defect in which the spine does not fully close around the spinal cord. With myelomeningocele the spine protrudes through the opening of the spinal column and may be enclosed in a fluid-filled sac. Spina bifida belongs to a class of birth defects called neural tube defects, which affect the brain and spine. The exposed spinal cord is susceptible to injury, which may result in weakness and

A study by researchers at the National Institutes of Health and the University of Oxford supports the widespread belief that stress may reduce a woman's chance of becoming pregnant. The study is the first of its kind to document, among women without a history of fertility problems, an association between high levels of a substance indicative of stress and a reduced chance of becoming pregnant.

Two findings from an NIH research network study provide new information on how much oxygen very preterm infants should receive starting on the first day of life and the most effective means to deliver it to them.

Working with mice, a team of researchers has pinpointed the location of bone generating stem cells in the spine, at the ends of shins, and in other bones. The team also has identified factors that control the stem cells' growth. The research was conducted at the National Institutes of Health and other institutions.

The more obese a woman is when she becomes pregnant, the greater the likelihood that she will give birth to an infant with a congenital heart defect, according to a study conducted by researchers at the National Institutes of Health and the New York state Department of Health.

Women can increase their chances for a healthy pregnancy by eating right, exercising, not smoking, and getting early medical care, says a podcast featuring a National Institutes of Health obstetrician who oversees research on pregnancy and birth.

Contrary to prevailing medical opinion, taking high doses of calcium during pregnancy does not prevent preeclampsia in women who do not have any risk factors for the disease, according to the largest, most comprehensive clinical trial of its kind to date.

Contrary to an earlier finding, inhaled nitric oxide therapy (a treatment for lung problems in premature infants) does not reduce the infant's chances for death or further lung problems, according to a study by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.

Multivitamin supplements containing high doses of the vitamin B complex, as well as vitamins C and E, given to HIV-infected women during pregnancy and for more than 5 years after they gave birth reduced the symptoms of AIDS, according to a study of Tanzanian women supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the John E. Fogarty International Center (FIC) for Advanced Study in the Health Sciences, both of the National Institutes of Health.

A team of researchers has discovered a gene for Cornelia de Lange Syndrome, a disorder consisting of mental retardation, heart defects and a number of physical abnormalities.

Newborns whose mothers drank alcohol heavily during pregnancy had damage to the nerves in the arms and legs, according to a study by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, one of the National Institutes of Health.