News

Researchers funded by the National Institutes of Health have discovered how a major pathway that initiates protein synthesis does so by using an enzyme as a go-between to activate the body’s internal clock.

When animals are present, children with autism spectrum disorders (ASDs) have lower readings on a device that detects anxiety and other forms of social arousal when interacting with their peers.

The National Institutes of Health has launched a subsite of DS-Connect: The Down Syndrome Registry for researchers, clinicians, and other professionals with a scientific interest in Down syndrome to access de-identified data from the registry.

Researchers from the National Institutes of Health have entered into an agreement with biotechnology company Vtesse, Inc., of Gaithersburg, Maryland, to develop treatments for Niemann-Pick disease type C (NPC) and other lysosomal storage disorders.

The NIH recently released Down Syndrome Directions: The National Institutes of Health Research Plan on Down Syndrome, an updated strategy to advance research related to Down syndrome.

For 2 days in April 2014, military families, researchers, educational and health care service providers, and other stakeholders came together on the NIH campus to talk about military families. They were participants in a conference on Military-Connected Children with Special Health Care Needs and Their Families.

More than 50 million Americans, about 1 in 5 people, are living with a disability. People with disabilities tend to be less physically active than people without disabilities and have higher rates of corresponding health problems such as obesity, heart disease, hypertension and stroke.

When researchers triggered an immune response in the wombs of pregnant mice, their offspring showed signs of brain damage that lasted well into adulthood. The animal’s hippocampus—that’s the part of the brain responsible for memory and spatial orientation—was smaller, and they had poor motor skills and behavioral issues, like hyperactivity.

Countless factors, from family and environment to genes and biology, influence a child’s growth and development. Scientists in the NICHD’s Section on Child and Family Research study how these factors affect the physical, mental, and social development of growing children, along with their health and well-being.

The National Institutes of Health is making funding awards of $35 million over the next five years to support the Centers for Collaborative Research in Fragile X program. Investigators at these centers will seek to better understand Fragile X-associated disorders and work toward developing effective treatments.

A recent survey shows that one in four young children (ages birth to 5) are at moderate to high risk for developmental, behavioral, or social delays.1 To raise awareness of these risks and promote early screening, the NICHD has joined the Administration for Children and Families and a number of other federal partners in launching Birth to 5: Watch Me Thrive!

Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches, researchers funded by the National Institutes of Health have found. Heritability also outweighed other risk factors in this largest study of its kind to date.

During Trisomy Awareness Month in March, the NICHD joins other organizations to raise awareness about trisomy conditions and the challenges they can pose to individuals and families.

The NIH Down Syndrome Working Group, formed in 2006 and led by the NICHD, aims to coordinate ongoing and new research related to Down syndrome across the NIH.

At the annual meeting of the Society for Neuroscience , held in San Diego, California, from November 9–13, more than 30,000 neuroscientists from around the world will share their latest research results and learn about new advances and opportunities in the field.

Researchers at the National Institutes of Health have identified a potential new drug that could help in the treatment of a form of Batten disease, a fatal childhood disorder. The researchers tested the drug in mice with the disease and found that it slowed the loss of coordination seen in the disorder, and extended the animals’ life span.

The NICHD has played a key role in the newborn screening activities and accomplishments of the last 5 decades and continues to lead and fund research activities related to newborn screening. As we mark the 50th anniversary of the dawn of the newborn screening era, the NICHD highlights some of its newborn screening research and accomplishments.

Understanding Down syndrome—its mechanisms, its effects on overall health, and ways to minimize its symptoms—has been an important part of the NICHD mission since it was established. The Institute is launching the DS-Connect®: The Down Syndrome Registry in an effort to create a centralized, secure national resource for storing and sharing health information about Down syndrome.

The National Institutes of Health has launched DS-Connect, a Web-based health registry that will serve as a national health resource for people with Down syndrome and their families, researchers, and health care providers.

Can sequencing of newborns’ genomes provide useful medical information beyond what current newborn screening already provides? Pilot projects to examine this important question are being funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the National Human Genome Research Institute (NHGRI), both parts of the National Institutes of Health.