News & Updates

Improved data reporting among the factors critical to reducing life-threatening complications of pregnancy and childbirth

Patient advocates, healthcare providers and researchers help map a future research agenda aimed at reducing maternal mortality and severe morbidity.

NICHD was established more than 50 years ago to help understand maternal health and improve pregnancy outcomes. These selected advances highlight NICHD’s contributions to advancing the health and well-being of pregnant women, mothers, and families everywhere.

Group seeks to enhance testing of therapeutics used by pregnant women and nursing mothers.

Each year in the United States, 700 women die from pregnancy or childbirth complications – one of the highest maternal death rates in the developed world. Listen to Milestones interview with Dr. Juanita Chinn from NICHD’s Population Dynamics Branch.

On April 8, 2019, join community organizations and healthcare professionals to discuss strategies for reducing the rising rate of maternal deaths in the United States.

Racial and ethnic disparities in severe maternal morbidity—life-threatening maternal complications associated with childbirth—have persisted and increased at high rates among U.S. women, according to an analysis of nearly 20 years of California hospital records funded by the National Institutes of Health.

The increasing rate in the United States of severe maternal morbidity—life-threatening maternal childbirth complications—may not be accounted for by the simultaneous increase in known risk factors for these complications, suggests an analysis of California hospital records funded by the National Institutes of Health. To reduce the rate of severe maternal morbidity, more research is needed to identify additional risk factors and other potential causes for the increase, the authors concluded.

Health experts recommend the seasonal flu shot for pregnant women.

Contrary to earlier studies, a National Institutes of Health funded analysis of records from more than 88,000 pregnancies in which women took the anti-nausea drug ondansetron found no increased risk for newborn heart malformations and only a slightly increased risk for cleft lip and palate.

In 2018, researchers funded by NICHD made significant progress in advancing the health and well-being of infants, children, teenagers, and adults across the United States and around the world.

A first-time mother’s risk of pelvic floor disorders is strongly associated with how her baby is delivered, according to a study funded by the National Institutes of Health. Pelvic floor disorders are thought to result from weakening or injury of the muscles, ligaments and connective tissue in the lowest part of the pelvis.

Maternal adipokines—molecules produced by fat cells—influence fetal growth and newborn length, birthweight, and proportion of body fat.

In studies of mice and nonhuman primates, researchers funded by the National Institutes of Health have used a technique known as RNA interference to reduce high levels of a protein that can cause preeclampsia, a potentially fatal high blood pressure disorder of pregnancy.

Compared to younger mothers, mothers over 35 are at higher risk of death and serious illness if they conceive 6 months or less after the birth of a previous child, according to a study funded in part by the National Institutes of Health. For mothers of all ages, such short intervals between pregnancies were associated with higher risk for preterm birth and for having infants small for their gestation age.

Collaboration with CDC aimed at evaluating pregnancy initiatives and outcomes

Delaying pushing during the second stage of labor—when the cervix is fully dilated at 10 centimeters—is a common practice at many U.S. hospitals, but it may have no effect on whether pregnant women deliver spontaneously (without a cesarean section or other intervention), according to a study funded by the National Institutes of Health.

NIH led task force submits recommendations on research needs for pregnant and nursing mothers

Healthy first-time mothers whose labor was induced in the 39th week of pregnancy were less likely to deliver by cesarean section, compared to those who waited for labor to begin naturally, according to a study funded by the National Institutes of Health.

The study seeks to determine if exposure poses a risk for neural tube defects.