Researchers funded by the National Institutes of Health have discovered the cellular switch that boosts the activity of sperm cells so that they can travel to the egg. The finding may lead to new options for male contraception as well as treatments for infertility resulting from problems with sperm mobility.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Only three genes needed for sperm production, mouse studies suggest
Recent NICHD-funded studies show in mice that only 3 genes are needed for sperm production, and the Y chromosome is not needed to make sperm precursors called spermatids. The findings may yield insight on potential treatments for male infertility.
Spotlight: NICHD Needs Your Input for the All of Us Research Program
NICHD needs your input for NIH’s All of Us program.
Trying to conceive soon after a pregnancy loss may increase chances of live birth
Couples who attempt to conceive within three months after losing an early pregnancy, defined as less than 20 weeks gestation, have the same chances, if not greater, of achieving a live birth than those who wait for three months or more, according to a National Institutes of Health study.
Infertility treatments do not appear to contribute to developmental delays in children
Children conceived via infertility treatments are no more likely to have a developmental delay than children conceived without such treatments, according to a study by researchers at the National Institutes of Health, the New York State Department of Health and other institutions.
Selected NICHD Research Advances of 2015
Over the past year, NICHD contributed to numerous scientific advances and key initiatives.
Blood test for chlamydia may predict pregnancy outcomes
A blood test that detects antibodies to the sexually transmitted bacterium Chlamydia trachomatis may be helpful in screening infertile women for pregnancy outcomes, according to a new study.
Q&A with NICHD Acting Director Catherine Spong, M.D.
Dr. Cathy Spong became NICHD’s acting director on October 1, 2015. Here she shares her plans for the year and her thoughts on what makes NICHD so unique.
Standard treatment better than proposed alternative for unexplained infertility
Treatment with clomiphene, a standard therapy for couples with unexplained infertility, results in more live births than treatment with a potential alternative, letrozole, according to a study of more than 900 couples conducted by a National Institutes of Health research network.
NICHD Supports Wide Range of Research on the Placenta
The placenta is a temporary organ that connects a mother and her fetus. It performs multiple functions, acting as the fetus’s lungs, kidneys, and liver, as well as the gastrointestinal, endocrine, and immune systems. It produces hormones to help maintain pregnancy and support fetal development, and it protects the fetus from the mother’s immune system. There is even a role for the placenta in determining the timing of birth.
Exploring Population Dynamics
NICHD’s Population Dynamics Branch supports research on a range of topics, including the factors that make populations rise and fall, such as fertility and mortality. We checked in with branch chief Rebecca Clark to learn more about the branch’s work.
NICHD grantees outline causes and treatments for infertility
For those who dream of being parents, pregnancy problems can be tremendously frustrating and disappointing. In recent decades, scientists have developed a wide range of approaches to help struggling couples have healthy babies. And NIH-funded studies are continuing to search for even better ways to overcome the challenges of infertility.
NIH launches new Spanish-language site for child health and human development
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH), has launched a Spanish-language website that provides free information on health topics, including maternal and infant care, obesity, HIV/AIDS, fertility/infertility, and pregnancy.
Promoting the Health of Women
NICHD conducts and supports research on health issues that are unique to women and on how certain diseases affect men and women differently.
2014 Annual Report of the Division of Intramural Research
NICHD’s Division of Intramural Research releases its 2014 annual report with progress updates from each program and laboratory.
Annual Report Highlights Population Health Research Findings
The NICHD’s Division of Intramural Population Health Research (DIPHR) provides research updates in its newly released annual report for 2014.
In Search of Answers for Those Struggling With Infertility
During National Infertility Awareness Week 2015, Dr. Alan Guttmacher explores the latest research in an article in the Huffington Po
Research Round-up: Endometriosis
Endometriosis is one of the most common gynecologic diseases, affecting an estimated 5 million women in the United States. The condition occurs when tissue that normally lines the inside of the uterus grows outside the uterus. Pain and infertility are its primary symptoms.
Physical labor, hypertension and multiple meds may reduce male fertility
Working in a physically demanding job, having high blood pressure, and taking multiple medications are among health risks that may undermine a man’s fertility, according to a study by researchers at the National Institutes of Health and Stanford University, Stanford, California.
Study finds genetic clue to menopause-like condition in young women
Six young women with a disorder that mimics menopause have gene alterations that hamper the repair of damaged DNA, report researchers supported by the National Institutes of Health.