In many poor countries, mothers with HIV face a stark choice: to nurse their infants, and risk passing on HIV through their breast milk--or to formula feed, and deprive their infants of much of the natural immunity needed to protect against fatal diseases of early infancy. Now, two studies supported by the National Institutes of Health offer insights into preventing early death and HIV infection among breastfeeding infants of mothers with HIV in these countries.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Focus on NICHD Women's Health Research
During Women’s Health Month, attention turns to the many advances in knowledge about women’s health as well as the gaps that remain in understanding many conditions. The NICHD was founded with a specific focus on women’s health as a way of understanding “the unsolved health problems of children and of mother-infant relationships.”
Mothers' High Normal Blood Sugar Levels Place Infants at Risk for Birth Problems
Pregnant women with blood sugar levels in the higher range of normal--but not high enough to be considered diabetes--are more likely than women with lower blood sugar levels to give birth to babies at risk for many of the same problems seen in babies born to women with diabetes during pregnancy, according to a study funded in large part by the National Institutes of Health.
Intensive Training for Medical Staff in Latin American Hospitals Reduces Serious Complication of Pregnancy
An intensive educational program for physicians and midwives involving 19 hospitals in Argentina and Uruguay dramatically reduced the rate of postpartum hemorrhage, according to researchers from the National Institutes of Health and other institutions.
Excess Fat Around the Waist May Increase Death Risk for Women
Women who carry excess fat around their waists were at greater risk of dying early from cancer or heart disease than were women with smaller waistlines, even if they were of normal weight, reported researchers from Harvard and the National Institutes of Health.
Gene Variation Predicts Response to Treatment in Common Infertility Disorder
NIH-sponsored researchers have discovered that women who have polycystic ovary syndrome (PCOS) are less likely to ovulate in response to a promising new drug treatment for the condition if they have a variation in a particular gene.
NIH Scientists Offer Explanation for Winter Flu Season
NIH Scientists Offer Explanation for Winter Flu Season Stability of Virus' Membrane at Cold Temperatures May Ease Winter Spread.
Older Mothers More Likely than Younger Mothers to Deliver By Caesarean
Researchers funded by the National Institutes of Health have found that older mothers with normal, full-term pregnancies-particularly first-time older mothers-were more likely to undergo Caesarean delivery than were younger women with similarly low-risk pregnancies.
Experimental Vaccine Given During Pregnancy Reduces Stillbirths from Common Virus
Researchers funded by the National Institutes of Health have developed an experimental vaccine that reduces stillbirths among rodents born to mothers infected with cytomegalovirus (CMV)--a common virus that can also cause mental retardation and hearing loss in newborn children who were infected in early fetal life.
Women's Response to Anti-HIV Therapy Improved If Treatment Begins Six Months After Earlier Preventive Regimen
A woman's response to HIV treatment with drug combinations that contain nevirapine is improved if at least six months have passed after she received the drug as a single dose during labor to prevent passing HIV on to her child. (The response to treatment is measured by the reduction of HIV in the blood.)
Hormonal Contraception Does Not Appear to Increase HIV Risk
Using hormonal contraception does not appear to increase women's overall risk of infection with the AIDS virus, report the authors of a large study commissioned by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.
Technology for Monitoring Fetal Oxygen During Labor Offers No Apparent Benefit
A new technology for measuring blood oxygen levels of a baby during labor--expected to provide information useful for preventing birth complications--offers no apparent benefit, report researchers in a National Institutes of Health research network.
Drug Prevents PostPartum Hemorrhage in Resource Poor Settings
The drug misoprostol provides a safe, convenient, and inexpensive means to prevent postpartum hemorrhage, a major killer of women in developing countries. The study was conducted by researchers from the University of Missouri, India's Jawaharlal Nehru Medical College, and the National Institutes of Health.
Pursuing the Causes of Preeclampsia
The basic research effort to implicate soluble endoglin (sEng) and soluble fms-like tyrosine kinase 1 (sFlt-1) in preeclampsia was led by a coauthor of the current paper, S. Ananth Karumanchi, M.D., a nephrologist at the Beth Israel Deaconess Medical Center in Boston.
New Findings Offer More Complete View Of Breast Cancer Gene Mutations in U.S. Population
A large study funded by the National Institutes of Health today provided the clearest picture yet of the prevalence in the U.S. population of mutations in two genes associated with an increased risk of breast cancer.
NIH - Study Finds Calcium Does Not Prevent Potentially Fatal Disorder of Pregnancy
Contrary to prevailing medical opinion, taking high doses of calcium during pregnancy does not prevent preeclampsia in women who do not have any risk factors for the disease, according to the largest, most comprehensive clinical trial of its kind to date.
Combined Surgery Reduces Incontinence in Women with Pelvic Organ Prolapse
By performing two surgical procedures during the same operation, researchers in an NIH network reduced by half the incidence of urinary incontinence in women with a condition known as pelvic organ prolapse.
Male Fat Distribution Pattern & Coronary Risk Profile Linked to X Chromosome
Two risk factors that place males at greater risk for heart disease than women appear to be influenced by genes on the X chromosome, report researchers at the NIH and the University of Texas Southwestern Medical School. The finding appears in a Research Letter in the Journal of the American Medical Association.
Drug Offers Alternative to Surgical Treatment After Miscarriage
A drug first used to reduce the risk of stomach ulcers in people taking certain types of painkillers offers an alternative to surgery after miscarriage, according to a study by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health and other research institutions.
Abused Women Less Likely to be Married or in Long-Term Relationships
Prevention of abuse would help women foster stable long-Term relationships. Women who experienced physical or sexual abuse in childhood or as adults are less likely to be married or in a stable long-term relationship than are other women, according to a large study of low-income women funded by the federal government.