News

Carriers of the FMR1 premutation—a mutation in the gene associated with the developmental disorder Fragile X syndrome—may have a higher risk for several health conditions, according to an analysis funded by the National Institutes of Health.

Infants born to mothers taking the drug naltrexone to treat opioid use disorder showed no signs of drug withdrawal and had shorter hospital stays than infants born to mothers undergoing the standard treatment, according to a small study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

Exposure to high levels of certain common air pollutants in early pregnancy may increase the risk of pregnancy-induced high blood pressure, suggests an analysis by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development. In addition, exposure to a class of air pollutants known as volatile organic compounds in mid-pregnancy may increase the risk for preeclampsia, a potentially fatal disorder of pregnancy affecting blood pressure and kidney function.

A high genetic risk score for cholesterol and other blood lipids among pregnant women is linked to fetal weight, but varies according to the mother’s racial and ethnic group and obesity status, suggests an analysis by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

Inherited genetic factors account for approximately 80 percent of the risk for autism spectrum disorder (ASD), according to estimates published in a study funded by NIH.

Finding may help find treatments for rare pituitary disorder

NIH-supported research calls for well-defined standards for infants between 6 months and 1 year

Children born to women on HIV therapy containing the drug dolutegravir since conception have a slightly higher risk of neural tube defects, compared to children born to women on regimens of other antiretroviral drugs.

Infants born to women exposed to high levels of air pollution in the week before delivery are more likely to be admitted to a newborn intensive care unit (NICU), suggests an analysis by researchers at the National Institutes of Health.

Low vitamin D levels at birth or in early childhood may increase the risk of high blood pressure in later childhood or adolescence, suggests a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the Health Resources and Services Administration.

Four NICHD grantees will be honored July 25 in Washington, DC, with the Presidential Early Career Award for Scientists and Engineers. More than 300 researchers across the country are award recipients, the White House announced July 2.

NICHD’s contributions to research on learning disabilities highlight decades of studies that informed the identification, recognition and treatment of these disorders.

Infants of the extinct human species Australopithecus africanus likely breast fed for up to a year after birth, similar to modern humans but of shorter duration than modern day great apes, according to an analysis of fossil teeth funded in part by the National Institutes of Health. The findings provide insight into how breast feeding evolved among humans and may inform strategies to improve modern breast-feeding practices.

Variants in the gene ARMC5 may be associated with high blood pressure among blacks, according to a National Institutes of Health study led by NICHD researchers.

Women who have gestational, or pregnancy-related, diabetes may be more likely to develop a potentially serious build up of fat in the liver later in life, suggests an analysis by researchers at the National Institutes of Health and other institutions. The researchers found that 9 to 16 years after pregnancy, women who had gestational diabetes have high levels of liver enzymes associated with the accumulation of fat, which could place them at risk of liver damage and liver failure.

Elevated blood pressure in the first trimester of pregnancy, or an increase in blood pressure between the first and second trimesters, raises the chances of a high blood pressure disorder of pregnancy, according to a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health.

A high genetic risk of obesity among pregnant women is linked to fetal weight, but varies according to race, fetal sex, and other factors, according to a study by researchers at the NICHD.

Preterm infants with a lower-than-normal growth rate have key differences in the bacteria and other organisms that live in their digestive tracts, according to a study funded by the NICHD. Moreover, byproducts of metabolism in slow-growing preterm infants are like those found in malnourished children, despite receiving a diet appropriate for their age.

Truvada, a drug combination that reduces the chances of HIV infection in high-risk people may result in small, yet persistent bone loss in younger adolescent males, suggests a study supported by the NICHD. The researchers added, however, that the protection against HIV offered by Truvada far outweighs any possible risks from bone loss.

Acceptance and support from communities and families appear to lessen the toll of mental health conditions experienced by former child soldiers transitioning to early adulthood, according to a study by researchers at the National Institutes of Health and other institutions.