News

U.S. rates of pregnancy-associated homicide—deaths that occur among women who are pregnant or had been pregnant within one year—rose in 2020 during the COVID-19 pandemic, according to a recent NICHD-funded study.

The experimental drug TEMPOL prevents viral replication and reduces disease severity in a hamster model of COVID-19, according to a new study led by NICHD.

Under appropriate conditions, protective face coverings can successfully be used during intelligence testing without interfering with the ability to understand the test administrator’s instruction, suggests a small study funded by the National Institutes of Health. Groups of young children scored comparably on a test measuring nonverbal intelligence whether they or the test administrators wore masks. The findings help to allay concerns that face masks may interfere with testing by hiding administrators’ facial expressions.

The Pfizer-BioNTech and Moderna COVID-19 vaccines may offer slightly more protection during pregnancy against SARS-CoV-2, compared to the Jansen/Johnson & Johnson vaccine, suggests a study funded by the National Institutes of Health. Vaccination during the first and third trimesters appears to result in higher antibody-stimulated immune responses than vaccination in the second trimester. It also may lead to greater transfer of antibodies from maternal blood to the placenta.

People who reported in survey that they felt worried, depressed or lonely had a greater chance of being hospitalized after a COVID-19 diagnosis, suggests a study funded by the National Institutes of Health.

Unlike other SARS-CoV-2 variants, the Delta variant can attach to copies of itself, forming larger aggregations, or clumps, of viral particles, suggests a study by scientists at the National Institutes of Health. The researchers theorize that this linking property may have played a role in the ability of the Delta variant to spread more rapidly than all the variants that preceded it.

Vaccination against COVID-19 appears to be safe for children who have had multisystem inflammatory syndrome in children (MIS-C) and does not appear to increase the risk for inflammation of the heart or other organs, suggests a small study funded by the National Institutes of Health. MIS-C, a serious inflammation of the heart, lungs, kidneys, brain, skin, eyes, gastrointestinal organs or other body parts, occurs in children about 4 to 6 weeks after COVID-19.

NIH-funded study compared more than 1.1 million students across nine states.

The COVID-19 pandemic has magnified mental and emotional health challenges for all of us. Dr. Bianchi highlights research to understand and address factors affecting the mental health of children and their parents.

Vaccinating women against SARS-CoV-2 in mid to late pregnancy could provide their infants at least some protection against COVID-19 through six months of age, suggests a small study funded by the National Institutes of Health. Compared to infants born to mothers who had COVID-19 during pregnancy, infants born to vaccinated mothers were much more likely to have antibodies against the virus.

Pregnant women with COVID-19 appear to be at greater risk for common pregnancy complications—in addition to health risks from the virus—than pregnant women without COVID-19, suggests a study funded by the National Institutes of Health.

Infants born during the pandemic—regardless of whether their mothers had COVID-19 during pregnancy—scored slightly lower on certain tests of neurodevelopment at 6 months old, compared to a similar group of infants born before the pandemic, according to a study funded by the National Institutes of Health. The findings suggest that children born during the pandemic may need long-term monitoring to rapidly identify any future lags in development. The researchers theorized that maternal stress resulting from the pandemic could have effects on children’s neurodevelopment.

COVID-19 vaccination does not affect the chances of conceiving a child, according to a study of more than 2,000 couples that was funded by the National Institutes of Health. Researchers found no differences in the chances of conception if either male or female partner had been vaccinated, compared to unvaccinated couples. However, couples had a slightly lower chance of conception if the male partner had been infected with SARS-CoV-2 within 60 days before a menstrual cycle, suggesting that COVID-19 could temporarily reduce male fertility.

Small NIH study contributes to understanding of COVID-19 during pregnancy.

Read about NICHD’s research findings and activities from 2021.

Women receiving one dose of a COVID-19 vaccine during a single menstrual cycle had an increase in cycle length of nearly one day, according to an NIH-funded study.

Dr. Bianchi discusses NICHD-led research on long COVID in children.

NIH commentary highlights community engagement in research design and implementation.

The National Institutes of Health will support a four-year follow-up study on the potential long-term effects of COVID-19 on women infected with SARS-CoV-2 during pregnancy. The study will also follow their offspring for any potential long-term effects.