The Maternal and Pediatric Infectious Disease Branch (MPIDB) was formed in 1988 as the Pediatric, Adolescent, and Maternal AIDS Branch. At that time, its mission was to support and conduct domestic and international research on the HIV/AIDS epidemic with a special focus on infants, children, adolescents, and women.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Chronic high blood sugar may be detrimental to the developing brain of young children
Young children who have long-term high blood sugar levels are more likely to have slower brain growth, according to researchers at centers including the National Institutes of Health.
Study finds genetic clue to menopause-like condition in young women
Six young women with a disorder that mimics menopause have gene alterations that hamper the repair of damaged DNA, report researchers supported by the National Institutes of Health.
Item of Interest: NIH Director Issues Statement on National Children’s Study
Today NIH Director Dr. Francis Collins issued a statement on the future of the National Children’s Study, following a report by the National Children's Study Working Group at a public meeting of the Advisory Committee to the Director.
NIH Updates Down Syndrome Research Plan
The NIH recently released Down Syndrome Directions: The National Institutes of Health Research Plan on Down Syndrome, an updated strategy to advance research related to Down syndrome.
NIH researchers link chromosome region to gigantism
Researchers at the National Institutes of Health have found a duplication of a short stretch of the X chromosome in some people with a rare disorder that causes excessive childhood growth. They believe that a single gene within the region likely has a large influence on how much children grow.
NICHD and HSC Foundation Event on Military-Connected Children with Special Needs
For 2 days in April 2014, military families, researchers, educational and health care service providers, and other stakeholders came together on the NIH campus to talk about military families. They were participants in a conference on Military-Connected Children with Special Health Care Needs and Their Families.
NICHD Co-Sponsors White House Disability Summit
More than 50 million Americans, about 1 in 5 people, are living with a disability. People with disabilities tend to be less physically active than people without disabilities and have higher rates of corresponding health problems such as obesity, heart disease, hypertension and stroke.
Nearly 55 percent of U.S. infants sleep with potentially unsafe bedding
Nearly 55 percent of U.S. infants are placed to sleep with bedding that increases the risk of sudden infant death syndrome, or SIDS, despite recommendations against the practice, report researchers at the National Institutes of Health, the Centers for Disease Control and Prevention, and other institutions.
High-tech analysis of genetic data may yield new test for endometriosis
Using sophisticated computer-based technology to analyze genetic data obtained from uterine tissue, researchers have identified patterns of genetic activity that can be used to diagnose endometriosis, an often-painful condition that occurs when tissue that normally lines the inside of the uterus grows outside the uterus. The prototype diagnostic method, developed with funding from the National Institutes of Health, can not only distinguish endometriosis from other disorders of the uterus, but can also identify the severity of the disease.
Brain abnormality found in group of SIDS cases
More than 40 percent of infants in a group who died of sudden infant death syndrome (SIDS) were found to have an abnormality in a key part of the brain, researchers report. The abnormality affects the hippocampus, a brain area that influences such functions as breathing, heart rate, and body temperature, via its neurological connections to the brainstem. According to the researchers, supported by the National Institutes of Health, the abnormality was present more often in infants who died of SIDS than in infants whose deaths could be attributed to known causes.
Mouse study reveals potential clue to extra fingers or toes
Researchers working with mice have uncovered a potential clue to polydactyly—a birth defect involving extra fingers on the hand or extra toes on the feet. The researchers have found that a mouse version of polydactyly results from a malfunction of the cellular machinery that processes one of the cell’s internal transportation vehicles.
NIH-sponsored study identifies superior drug regimen for preventing mother-to-child HIV transmission
For HIV-infected women in good immune health, taking a three-drug regimen during pregnancy prevents mother-to-child HIV transmission more effectively than taking one drug during pregnancy, another during labor and two more after giving birth, an international clinical trial has found.
NICHD Funds Research on Traumatic Brain Injury (TBI)
TBIs and concussions get a lot of attention in the news. In football players at all levels, repeated concussions have been linked to long-term health problems. Veterans have come back from wars with brain injuries caused by explosions. TBIs also happen in daily life. Children fall on the playground, and elderly people have balance problems that lead to more falls. As common as TBIs are, though, there is still much to learn about how to treat these injuries and how to deal with related problems over the long term.
NIH study links ultraviolet filters to pregnancy delays
Certain sunscreen chemicals used to protect against ultraviolent rays may impair men’s ability to father children in a timely manner, according to a study by the National Institutes of Health and the New York state Department of Health’s Wadsworth Center. But the researchers caution that the results are preliminary and that additional studies are needed to confirm their findings.
20 Years of Protecting Infants During Sleep
NICHD Director Dr. Alan Guttmacher recently published an article in the Huffington Post about the Institute’s efforts to reduce the risk of Sudden Infant Death Syndrome (SIDS) and promote safe infant sleep. In the article, he highlighted the NICHD’s research activities related to SIDS and the contributions of the NICHD-led Safe to Sleep® campaign, which recently celebrated its 20th anniversary. He also talked about how SIDS has affected his own family.
Inflammation in womb affects brain, behavior of baby mice
When researchers triggered an immune response in the wombs of pregnant mice, their offspring showed signs of brain damage that lasted well into adulthood. The animal’s hippocampus—that’s the part of the brain responsible for memory and spatial orientation—was smaller, and they had poor motor skills and behavioral issues, like hyperactivity.
Parents’ Response to Baby’s Babbling Can Speed Language Development
A new study suggests that how parents respond to their infants’ babbling sounds may foster their infants’ language skills. Playfully mimicking or returning infant babbling lets the child know that he or she can communicate, and this knowledge helps the infant learn the complex sounds that make up speech.
A Look Inside the Brain
Traumatic brain injury (TBI) can happen to anyone, at any age. Approximately 1.7 million people experience a TBI in the United States each year; about 53,000 die from TBI-related causes.
Pregnancy Lifestyle Influences Gestational Diabetes Risk
Nearly half of all cases of diabetes during pregnancy could be prevented if the expecting mothers ate well, exercised regularly, stopped smoking, and maintained a healthy body weight before pregnancy, a new study finds.