The National Institutes of Health has developed a research plan to advance the understanding of fragile X syndrome and its associated conditions, fragile X-associated tremor/ataxia syndrome and fragile X-associated primary ovarian insufficiency. Fragile X syndrome causes intellectual and developmental disabilities and results from a mutation in a gene on the X chromosome.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
New Technique Could Sustain Cancer Patients' Fertility
Researchers funded by the National Institutes of Health have completed a critical first step in the eventual development of a technique to retain fertility in women with cancer who require treatments that might otherwise make them unable to have children.
NIH Podcast Advises Women On How to Achieve a Healthy Pregnancy
Women can increase their chances for a healthy pregnancy by eating right, exercising, not smoking, and getting early medical care, says a podcast featuring a National Institutes of Health obstetrician who oversees research on pregnancy and birth.
Researchers Identify Key Proteins Needed for Ovulation
Researchers from the National Institutes of Health and other institutions have identified in mice two proteins essential for ovulation to take place.
Researchers Develop DNA "Patch" For Canine Form of Muscular Dystrophy
Using a novel genetic technology that covers up genetic errors, researchers funded in part by the National Institutes of Health have developed a successful treatment for dogs with the canine version of Duchenne muscular dystrophy, a paralyzing, and ultimately fatal, muscle disease.
Earlier Jaundice Treatment Decreases Brain Injury In Preemies
A study from a National Institutes of Health research network found that an early treatment to prevent severe newborn jaundice in extremely early preterm infants reduced the infants' rate of brain injury, a serious complication of severe jaundice.
The National Institutes of Health and Jackson Medical Mall Launch Informative Health Series for Mississippians
The NIH/Jackson Medical Mall health information series will provide residents of the Jackson, Miss., area with informational presentations on diabetes, stroke/hypertension, asthma, and mental health. The health series will also include quarterly continuing medical education (CME) presentations for health care professionals.
Roughly One Quarter of U.S. Women Affected by Pelvic Floor Disorders
Nearly 24 percent of U.S. women are affected with one or more pelvic floor disorders, report researchers funded by the National Institutes of Health. Their analysis is the first to document in a nationally representative sample the extent of pelvic floor disorders, a cluster of health problems that causes physical discomfort and limits activity.
Common Treatment to Delay Labor Decreases Preterm Infants' Risk for Cerebral Palsy
Preterm infants born to mothers receiving intravenous magnesium sulfate--a common treatment to delay labor--are less likely to develop cerebral palsy than are preterm infants whose mothers do not receive it, report researchers in a large National Institutes of Health research network.
Findings Offer Insights into Role of Breastfeeding in Preventing Infant Death, HIV Infection in Resource Poor Countries
In many poor countries, mothers with HIV face a stark choice: to nurse their infants, and risk passing on HIV through their breast milk--or to formula feed, and deprive their infants of much of the natural immunity needed to protect against fatal diseases of early infancy. Now, two studies supported by the National Institutes of Health offer insights into preventing early death and HIV infection among breastfeeding infants of mothers with HIV in these countries.
NIH Researchers Find That Rett Syndrome Gene Is Full of Surprises
A study funded by the National Institutes of Health (NIH) has transformed scientists' understanding of Rett syndrome, a genetic disorder that causes autistic behavior and other disabling symptoms. Until now, scientists thought that the gene behind Rett syndrome was an "off" switch, or repressor, for other genes. But the new study, published today in Science1, shows that it is an "on" switch for a startlingly large number of genes.
Mothers' High Normal Blood Sugar Levels Place Infants at Risk for Birth Problems
Pregnant women with blood sugar levels in the higher range of normal--but not high enough to be considered diabetes--are more likely than women with lower blood sugar levels to give birth to babies at risk for many of the same problems seen in babies born to women with diabetes during pregnancy, according to a study funded in large part by the National Institutes of Health.
Intensive Training for Medical Staff in Latin American Hospitals Reduces Serious Complication of Pregnancy
An intensive educational program for physicians and midwives involving 19 hospitals in Argentina and Uruguay dramatically reduced the rate of postpartum hemorrhage, according to researchers from the National Institutes of Health and other institutions.
Gene Variation Predicts Response to Treatment in Common Infertility Disorder
NIH-sponsored researchers have discovered that women who have polycystic ovary syndrome (PCOS) are less likely to ovulate in response to a promising new drug treatment for the condition if they have a variation in a particular gene.
Tobacco Use, Secondhand Smoke Exposure during Pregnancy, May Threaten Health of Women & Children in Developing Nations
Findings from a National Institutes of Health (NIH) study indicate that rates of tobacco use during pregnancy, as well as exposure of pregnant women and their young children to secondhand smoke, are significant threats to health in several low and middle-income countries.
Extended Nevirapine Regimens Reduce HIV Transmission and Death in Breastfed Infants of HIV-infected Mothers
An extended course of the antiretroviral drug nevirapine (NVP) helps the breastfeeding babies of HIV-infected mothers remain HIV-negative and live longer, according to several new studies presented at the 15th Conference on Retroviruses and Opportunistic Infections held in Boston from February 3-6.
The Post-Exposure Prophylaxis of Infant (PEPI)-Malawi Study Sponsored by NICHD and CDC
Questions and Answers.
NIH Develops Down Syndrome Research Plan
The National Institutes of Health has developed a research plan to advance understanding of Down syndrome and speed development of new treatments for the condition, the most frequent genetic cause of mild to moderate intellectual disability and associated medical problems. The plan sets research goals for the next 10 years that build upon earlier research advances fostered by the NIH.
Milk Matters Online Lesson Resources Available for Teachers
New online resources stressing the importance of calcium for bone health are now available for middle and high school teachers. The resources are available through the Milk Matters calcium education campaign, sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.
Researchers Discover Gene For Rare Skin Disorder
Researchers funded in part by the National Institutes of Health have identified the gene that accounts for most cases of Goltz syndrome, a rare skin disorder that can also affect bone and eye development.