News & Updates

The antiretroviral drugs used to keep HIV at bay are an unqualified success at preventing the spread of the virus from mother to child. The drugs are not only essential for maintaining the health of a pregnant woman with HIV, they have also nearly eliminated the transmission of HIV to her baby. Among U.S. women, the likelihood of a mother passing the virus on to her child is now less than 1%.

Birth control pills are less effective for obese women. Studies have shown that obesity brings with it hormonal changes that can reduce the pill’s effectiveness.

The next NICHD Director’s Lecture at the NIH will feature Diana Bianchi, M.D., from Tufts University School of Medicine. Her talk, titled “Changing Paradigms: From Prenatal Genetic Diagnosis to Fetal Individualized Medicine,” will take place on January 21, 2015, 9:00–10:00 a.m., in Lipsett Amphitheater, at NIH’s Clinical Center in Bethesda, Md.

The standard treatment for newborns whose brains were deprived of oxygen appears to work better than proposed alternatives, according to a study from a National Institutes of Health research network.

Young children who have long-term high blood sugar levels are more likely to have slower brain growth, according to researchers at centers including the National Institutes of Health.

Six young women with a disorder that mimics menopause have gene alterations that hamper the repair of damaged DNA, report researchers supported by the National Institutes of Health.

More than 50 million Americans, about 1 in 5 people, are living with a disability. People with disabilities tend to be less physically active than people without disabilities and have higher rates of corresponding health problems such as obesity, heart disease, hypertension and stroke.

Nearly 55 percent of U.S. infants are placed to sleep with bedding that increases the risk of sudden infant death syndrome, or SIDS, despite recommendations against the practice, report researchers at the National Institutes of Health, the Centers for Disease Control and Prevention, and other institutions.

Using sophisticated computer-based technology to analyze genetic data obtained from uterine tissue, researchers have identified patterns of genetic activity that can be used to diagnose endometriosis, an often-painful condition that occurs when tissue that normally lines the inside of the uterus grows outside the uterus. The prototype diagnostic method, developed with funding from the National Institutes of Health, can not only distinguish endometriosis from other disorders of the uterus, but can also identify the severity of the disease.

More than 40 percent of infants in a group who died of sudden infant death syndrome (SIDS) were found to have an abnormality in a key part of the brain, researchers report. The abnormality affects the hippocampus, a brain area that influences such functions as breathing, heart rate, and body temperature, via its neurological connections to the brainstem. According to the researchers, supported by the National Institutes of Health, the abnormality was present more often in infants who died of SIDS than in infants whose deaths could be attributed to known causes.

Researchers working with mice have uncovered a potential clue to polydactyly—a birth defect involving extra fingers on the hand or extra toes on the feet. The researchers have found that a mouse version of polydactyly results from a malfunction of the cellular machinery that processes one of the cell’s internal transportation vehicles.

For HIV-infected women in good immune health, taking a three-drug regimen during pregnancy prevents mother-to-child HIV transmission more effectively than taking one drug during pregnancy, another during labor and two more after giving birth, an international clinical trial has found.

When researchers triggered an immune response in the wombs of pregnant mice, their offspring showed signs of brain damage that lasted well into adulthood. The animal’s hippocampus—that’s the part of the brain responsible for memory and spatial orientation—was smaller, and they had poor motor skills and behavioral issues, like hyperactivity.

A new study suggests that how parents respond to their infants’ babbling sounds may foster their infants’ language skills. Playfully mimicking or returning infant babbling lets the child know that he or she can communicate, and this knowledge helps the infant learn the complex sounds that make up speech.

Researchers have used brain scans to track how young children learn to read, raising the possibility that the method could be used to diagnose young children with dyslexia and other reading disorders before they experience problems in school. Once identified, the children could be fast-tracked to interventions designed to help them overcome their reading difficulties.

World population is likely to keep growing throughout the 21st century, reaching 11 billion by 2100, according to results of a new study. That’s about 2 billion higher than previous estimates. The revised forecast uses statistical methods to combine government data and expert forecasts for trends such as mortality rates, fertility rates, and international migration.

A study by a National Institutes of Health research network calls into question plans to increase access to steroid treatment for pregnant women in low resource settings at high risk for preterm birth. The study concluded that the treatment—a standard, life-saving practice in high income countries such as the United States—could potentially cause harm in low resource settings where many births take place outside the advance care hospitals that are standard in high income countries.

It’s normal for most women to gain weight during pregnancy, but gaining too much weight can pose serious health risks for mother and baby. Now researchers funded in part by the National Institutes of Health have found that an integrated program offering support and nutrition counseling succeeds where the traditional approaches failed and helps keep women from adding too much weight during pregnancy.

The National Institutes of Health is making funding awards of $35 million over the next five years to support the Centers for Collaborative Research in Fragile X program. Investigators at these centers will seek to better understand Fragile X-associated disorders and work toward developing effective treatments.

Using a teaspoon or a tablespoon to give children medicine doubled parents’ chances of giving an incorrect dose, according to researchers funded by the National Institutes of Health.