News

The National Institutes of Health has announced research funding to encourage the development of approaches that identify children at high risk for developing Multisystem Inflammatory Syndrome in Children (MIS-C), thought to be a severe complication of COVID-19. Up to $20 million will be awarded to successful research proposals over four years.

Scoring system developed by NIH-funded researchers standardizes patient data to aid research, surveillance and improvement initiatives.

NICHD has supported gynecologic and reproductive health research for decades. Learn more about its leading role in menstruation research.

The placental membranes that contain the fetus and amniotic fluid lack the messenger RNA (mRNA) molecule required to manufacture the ACE2 receptor, the main cell surface receptor used by the SARS-CoV-2 virus to cause infection, according to a study by researchers at the National Institutes of Health.

In a study of mice, NIH-funded researchers have developed a prototype technique for shrinking uterine fibroids—sometimes painful, noncancerous tumors that form in the uterus. The method involves encasing a tumor-killing drug in nano-sized spheres called liposomes and delivering them directly to the fibroids through the bloodstream. The findings set the stage for studies to determine if the method is safe and effective for treating fibroids in people.

Screen time before bed may affect kids differently, depending on whether they have a particular personality trait, suggests a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Nighttime electronic media use was linked to less sleep in children who scored lower on a measure of effortful control—the ability to override inappropriate impulses, focus attention, and complete difficult tasks. In contrast, bedtime screen use was not associated with sleep reduction in children who scored high in effortful control.

Polycystic ovary syndrome, an infertility disorder affecting at least 15% of reproductive-age women, may have at least two different subtypes, suggests a study funded by the National Institutes of Health. The findings could provide important information on the possible causes of PCOS and for developing more effective ways to treat the condition.

A mouse study funded by the National Institutes of Health suggests that a step in the in vitro fertilization (IVF) procedure could account for the higher rate of complications in pregnancies resulting from this form of assisted reproductive technology (ART). The researchers linked the culture of embryos in laboratory dishes after fertilization with impaired growth of the placenta, smaller fetal size, and a higher risk of preeclampsia, a serious pregnancy-related blood pressure disorder.

DNA from uterine cells of women with endometriosis has different chemical modifications, compared to the DNA of women who do not have the condition, according to researchers funded by the National Institutes of Health. The changes involve DNA methylation—the binding of compounds known as methyl groups to DNA—which can alter gene activity.

Compared to other women, deaf and hard of hearing women have a higher risk for pregnancy and birth complications such as gestational diabetes and blood pressure disorders, according to a study funded by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development. Moreover, infants of deaf and hard of hearing women were more likely to be born preterm, have low birth weight, and receive a low Apgar score—a screening test used to determine the baby’s need for additional medical services.

Researchers funded by the National Institutes of Health have launched an effort to evaluate drugs prescribed to treat COVID-19 in infants, children and adolescents across the country.

Waiting 28 days to give iron supplements to malaria-infected children with a severe low red blood cell count (anemia) may improve their iron levels a year later, according to a study funded by the National Institutes of Health.

Environmental, biological samples span the period from preconception to early childhood.

Researchers supported by the National Institutes of Health and the Bill & Melinda Gates Foundation will assess whether a single oral dose of the antibiotic azithromycin during labor reduces the risk of maternal and infant bacterial infection and death in seven low- and middle-income countries.

Teens who take positive risks, such as enrolling in a challenging course or initiating a new friendship, tend to be more involved in school and less likely to act impulsively, compared to those who take negative risks like drinking alcohol or stealing, according to a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health.

Researchers to evaluate medical records of 21,000 pregnant women

Roughly 3 to 5% of children with an aunt or uncle with autism spectrum disorder (ASD) can also be expected to have ASD, compared to about 1.5% of children in the general population, according to a study funded by the National Institutes of Health. The findings call into question the female protective effect, a theory that females have a lower rate of ASD than males because they have greater tolerance of ASD risk factors.

An NIH-funded study found that youth with Fragile X syndrome experienced verbal improvements from a parent-based language intervention, but a drug treatment paired with the intervention did not provide additional benefit.

Program will include lessons learned from caring for pregnant women with COVID-19.

A small study funded by the National Institutes of Health suggests that sleep problems among children who have a sibling with autism spectrum disorder (ASD) may further raise the likelihood of an ASD diagnosis, compared to at-risk children who do not have difficulty sleeping.