News & Updates

Hydrocortisone is no more effective than placebo at preventing damage that can result from oxygen and ventilator therapy necessary to keep preterm infants alive, according to research funded by the National Institutes of Health. The study of a potential treatment for the condition, known as bronchopulmonary dysplasia, appears in the New England Journal of Medicine.

To help spur innovation against a growing maternal health crisis, NICHD launched the Decoding Maternal Morbidity Data Challenge last year. Learn about the winning proposals.

Researchers funded by the National Institutes of Health have developed a prototype genetic test with the potential to predict the development and eventual severity of uterine fibroids—benign, but sometimes painful and debilitating tumors of the uterus. The test could be used to identify fibroid cases early and to better understand how they develop and how to treat them.

NIH-funded study compared more than 1.1 million students across nine states.

Life-threatening pregnancy complications known as severe maternal morbidity (SMM) appear to be associated with an increased length of hospital stay for infants and an increase in the cost of caring for them, suggests a study funded by the National Institutes of Health. The findings support the hypothesis that infants of mothers with SMM may also be at risk for severe complications. The authors concluded that helping patients to reduce their risk factors—in early pregnancy or before conception—may reduce the chances for SMM and improve the health of infants.

In the United States, more than 20 percent of deaths during pregnancy and the first year after childbirth are due to drug use, suicide, or homicide, an NICHD-funded study suggests. The number of pregnancy associated deaths from these causes increased between 2010 and 2019, with drug-related deaths nearly tripling.

Vaccinating women against SARS-CoV-2 in mid to late pregnancy could provide their infants at least some protection against COVID-19 through six months of age, suggests a small study funded by the National Institutes of Health. Compared to infants born to mothers who had COVID-19 during pregnancy, infants born to vaccinated mothers were much more likely to have antibodies against the virus.

Pregnant women with COVID-19 appear to be at greater risk for common pregnancy complications—in addition to health risks from the virus—than pregnant women without COVID-19, suggests a study funded by the National Institutes of Health.

Infants born during the pandemic—regardless of whether their mothers had COVID-19 during pregnancy—scored slightly lower on certain tests of neurodevelopment at 6 months old, compared to a similar group of infants born before the pandemic, according to a study funded by the National Institutes of Health. The findings suggest that children born during the pandemic may need long-term monitoring to rapidly identify any future lags in development. The researchers theorized that maternal stress resulting from the pandemic could have effects on children’s neurodevelopment.

Women who breastfed for two years or longer had higher blood levels of anti-Müllerian hormone and later onset of menopause, compared to women who breastfed for one month or less, according to an NICHD-supported analysis. The findings also suggest that previously observed relationships between menopause timing and the number of times a woman gave birth may be largely attributable to breastfeeding.

A new study funded by the National Institutes of Health contradicts the current recommendation that women with obesity should lose weight before trying to conceive. The study of more than 300 women with obesity found no difference in the proportion of live births among women with unexplained infertility who lost weight before infertility treatment and a similar group who did not lose weight before treatment.

Taking supplemental docosahexaenoic acid (DHA) during pregnancy may decrease the risk of preterm birth. A new NICHD-supported study offers a potential explanation for this effect by suggesting that a daily 1,000-milligram dose of DHA influences certain inflammatory immune responses linked to childbirth.

COVID-19 vaccination does not affect the chances of conceiving a child, according to a study of more than 2,000 couples that was funded by the National Institutes of Health. Researchers found no differences in the chances of conception if either male or female partner had been vaccinated, compared to unvaccinated couples. However, couples had a slightly lower chance of conception if the male partner had been infected with SARS-CoV-2 within 60 days before a menstrual cycle, suggesting that COVID-19 could temporarily reduce male fertility.

The survival rate of extremely preterm infants born from 2013 through 2018 in a large network of U.S. research centers improved to 78.3%, compared to 76% for infants born in the network from 2008 to 2012, according to researchers funded by the National Institutes of Health.

Read about NICHD’s research findings and activities from 2021.

More than a third of U.S. physicians do not know their legal requirements under the Americans with Disabilities Act (ADA), the federal civil rights law that prohibits discrimination against individuals with disabilities, according to a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). More than 70% of physicians did not know that they share responsibility with patients to determine reasonable accommodations—how to adjust policies, practices, and procedures to ensure patient care.

Women receiving one dose of a COVID-19 vaccine during a single menstrual cycle had an increase in cycle length of nearly one day, according to an NIH-funded study.

Sleep-disordered breathing in early pregnancy is associated with insulin resistance or difficulty clearing glucose from the blood, suggests a small study funded by the National Institutes of Health. The results strengthen the link between sleep-disordered breathing, which includes pauses or slowing of breathing during sleep, and gestational diabetes. They also suggest that screening pregnant women, particularly those with overweight or obesity, for sleep-disordered breathing could identify those who might benefit from early interventions to reduce their diabetes risk.

It just got easier to participate in the PregSource®: Crowdsourcing to Understand Pregnancy research project. The free app allows participants to track their weight, sleep, mood, and other features of their pregnancy in just a few taps.

Dr. Bianchi discusses NICHD-led research on long COVID in children.