The NICHD conducts and supports a variety of clinical research related to high-risk pregnancy. Select a link below to learn more about these projects.
Featured NICHD Clinical Trials on High-Risk Pregnancy
Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
Infants born between 34 and 36 weeks of gestation, known as "late preterm," are more likely to be admitted to a special care nursery and more likely to have respiratory complications than infants born at term. The use of antenatal corticosteroids has been shown to improve lung function in very premature infants but has not been evaluated in those likely to deliver in the late preterm period. This research study aims to answer the following primary research question: Do steroids, compared with no steroids, decrease infants’ need for oxygen support when given to pregnant women at least 12-24 hours before they deliver at 34 weeks to 36 weeks gestation? The research study will also collect information on whether steroids improve the chances that the infant will not get sick from other causes.
NICHD Clinical Trials
ClinicalTrials.gov Search Results
Information on current NIH-sponsored clinical trials on high-risk pregnancy is available at the link below or by calling 800-411-1222.