Pituitary tumors and other endocrine tumors lead to a variety of health problems in adults and children. NICHD research efforts include uncovering the genetic abnormalities and molecular mechanisms that underlie the development of pituitary tumors and related syndromes. Clinical studies in progress aim to uncover methods for diagnosing, managing, and treating pituitary tumors in children. The Institute also supports professional training and the development of research infrastructure that will facilitate investigations into childhood pituitary tumors.