PCOS is a set of symptoms related to a hormonal imbalance. Symptoms can affect metabolic, cardiovascular, inflammatory, reproductive, and other aspects of health. PCOS may cause menstrual cycle changes; skin changes such as increased facial and body hair and acne; growths in one or both ovaries, often clumps of ovarian follicles that have stopped developing; and infertility. People with PCOS may also have metabolic issues, such as insulin resistance or obesity.