The NICHD conducts and supports a variety of clinical research related to menstruation and menstrual irregularities. Select a link below to learn more about these projects.
Featured NICHD Clinical Trials on Menstrual Irregularities
- Pelvic Pain from Endometriosis
To determine if botulinum toxin can relieve pain from pelvic floor spasm in women with pelvic pain, researchers are studying Botulinum Toxin for Pelvic Pain in Women With Endometriosis. The chronic pelvic pain that some women with endometriosis experience may be caused by spasms of the pelvic floor muscles. Because studies suggest that botulinum toxin can help treat muscle spasm problems, researchers are studying whether botulinum toxin injections into the pelvic floor muscles can decrease pain and spasms in these women.
- Abnormal Uterine Bleeding in Premenopausal Women
In previous studies, a hormone that blocks progesterone and is necessary for maintaining pregnancy, CDB-2914, was shown to shrink the tumor size in women with uterine fibroids. In many cases, menstrual periods stopped during treatment. Because CDB-2914 decreased or stopped menstrual bleeding in women with uterine fibroids, it may also be able to treat abnormal periods in women without fibroids. CDB-2914 for Abnormal Uterine Bleeding in Premenopausal Women will study whether CDB-2914 can treat abnormal uterine bleeding in premenopausal women.
- Inherited Reproductive Disorders
The transition from childhood to adulthood occurs during puberty, and problems with the hormones released during puberty can affect the reproductive system. Some children have low hormone levels that severely delay or prevent the onset of puberty; others start puberty abnormally early. Conversely, children who have a normal puberty may develop reproductive disorders later in life. The Inherited Reproductive Disorders study will look at people with reproductive disorders to learn more about how these disorders may be inherited.
NICHD Clinical Trials
Information on current NIH-sponsored clinical trials on menstrual irregularities is available at the link below or by calling 800-411-1222.
All NICHD Clinical Trials on "menstruation or "menstrual cycle"
All NICHD Clinical Trials on "menstrual irregularities"
ClinicalTrials.gov Search Results
All ClinicalTrials.govTrials on "menstruation or "menstrual cycle"
All ClinicalTrials.gov Trials on "menstrual irregularities"