Down Syndrome: Clinical Trials

The NICHD conducts and supports a variety of clinical trials related to Down syndrome.

Featured NICHD Clinical Trials on Down Syndrome

• Multicenter Vitamin E Trial in Aging Persons with Down Syndrome. The goal of this study is to determine the safety and efficacy of the administration of vitamin E in slowing the rate of cognitive/functional decline in older persons with Down syndrome. Vitamin E is being used in this study because it has been shown to delay the progression of Alzheimer's disease. Researchers want to examine if it can also help people with Down syndrome.
• History of Amyloid Deposition in Adults with Down Syndrome. The purpose of this study is to identify the nature, cause, and outcome of decreased cognitive performance in adults with Down syndrome. The primary objective is to assess the presence of amyloid deposition in non-demented/functionally stable adults with Down syndrome as a function of age and to obtain baseline cognitive measures across a range of areas that are often affected by Alzheimer's disease.

NICHD Clinical Trials

Information on all current NIH-sponsored clinical trials on Down syndrome is available at the links below or by calling 800-411-1222.

• All NICHD Clinical Trials on Down syndrome

ClinicalTrials.gov Search Results

• All ClinicalTrials.gov Trials on Down syndrome