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Overview
Chris McBain's Section on Cellular and Synaptic Physiology, investigates the development and regulation of cortical excitability, in particular glutamatergic and GABAergic synaptic transmission and plasticity in the hippocampal formation. The Section investigates mechanisms underlying the differential regulation of transmitter release at functionally divergent presynaptic terminals along a common axon, the roles of ionotropic and metabotropic glutamatergic and cholinergic receptors in controlling cell excitability, and bi-directional synaptic plasticity at both inhibitory and excitatory axon terminals.