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Leikin Lab: Section on Physical Biochemistry

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Scientific Resources

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Projects:

Collagen and proteoglycan related diseases

  • Collagen folding, stability and interactions
  • Osteogenesis Imperfecta
  • Ehlers-Danlos syndrome
  • Collagen and proteoglycan pathology in fibrosis and cancer
  • Chondrodysplasias
  • Osteoporosis and osteoarthritis

High-definition micro-spectroscopic imaging and analysis of biomaterials

  • High-definition micro-spectroscopic imaging technology
  • Real-time, label-free imaging of biochemical reactions in tissue sections and live cell cultures

Physics of biological helices

  • Molecular structure and electrostatic interactions
  • Chiral forces in supercoiling
  • Theory of cholesteric phases

Homologous pairing of DNA

  • Sequence homology recognition between DNA double helices in vitro
  • Pairing of homologous DNA in vivo
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Last Updated Date: 11/30/2012

​Contact Information

Name: Dr Sergey Leikin
Senior Investigator
Section on Physical Biochemistry
Phone: 301-594-8314
Fax: 301-402-0292
E-mail: leikins@mail.nih.gov

Staff Directory
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