CURRICULUM VITAE Wei Bao, M.D., Ph.D.

Updated: July, 2012

Postdoctoral fellow
Epidemiology Branch, Division of Epidemiology, Statistics, and Preventive Research
Eunice Kennedy Shriver National Institute of Child Health and Human Development
National Institutes of Health (NIH)
6100 Executive Blvd., Room 7B03, Rockville, MD 20852, USA
Phone: 301-402-6831; Email: baow2@mail.nih.gov

EDUCATION BACKGROUND

Sep. 2008-June 2011

Ph.D. in Nutrition and Food Hygiene

Tongji Medical College,

Huazhong University of Science & Technology

Sep. 2006-June 2008

MMed (M.PH. equivalent) in Nutrition and Food Hygiene

Tongji Medical College,

Huazhong University of Science & Technology

Mar. 2003-June 2006

BSc (Bachelor of Science) in Biological Science

College of Life Sciences,

Wuhan University

Sep. 2001-June 2006

MBBS (M.D. equivalent) in Preventive Medicine

Tongji Medical College,

Huazhong University of Science & Technology

ACADEMIC TRAINING EXPERIENCE

PROFESSIONAL EXPERIENCE

MEMBERSHIP

HONORS & AWARDS

  1. Intramural Research Training Awards, granted by National Institutes of Health (NIH), 2011-2013

  2. Travel Grant Award for the 21th World Diabetes Congress held by the International Diabetes Federation (IDF) in Dubai, United Arab Emirates, 2011

  3. Qiu Fazu Scholarship Award, granted by Qiu Fazu Foundation, P.R. China, 2011

  4. Scholarship Award for Excellent Doctoral Student, granted by Ministry of Education, P.R. China, 2010

  5. Outstanding Investigator Award for Top Ten Graduate Students, granted by Huazhong University of Science & Technology, 2010

  6. Outstanding Principal Investigator for Programs Funded by the Graduates' Innovation Fund of Huazhong University of Science & Technology, 2010

  7. Travel Grant Award and Pfizer Emerging Scientist Award for the 20th World Diabetes Congress held by the International Diabetes Federation (IDF) in Montreal, Canada, 2009

  8. Travel Grant Award for the 19th Conference of the Asian Pacific Association for the Study of the Liver (APASL) in Hong Kong SAR, 2009

  9. Outstanding Graduate Student Leader Award, granted by Huazhong University of Science & Technology, 2008-2009, 2006-2007

  10. Outstanding Student Award, granted by Huazhong University of Science & Technology, 2004-2005, 2003-2004

  11. National Outstanding Student Award, granted by Ministry of Education, P.R. China, 2003-2004

  12. Outstanding Undergraduate Student Leader Award, granted by Huazhong University of Science & Technology, 2002-2003

  13. President of Tongji Volunteers Association, Tongji Medical College, Huazhong University of Science & Technology, 2002-2003

  14. Secretary-General of Student Union, Tongji Medical College, Huazhong University of Science & Technology, 2002-2003

RESEARCH PROGRAMS

Ongoing Research Programs

  1. “Supplemental Iron and Gestational Diabetes”, funded by the Office of Dietary Supplements (ODS), NIH, 2012-2013. (My role: PI)

  2. “Diabetes and Women’s Health- a study of long-term health implications of glucose intolerance in pregnancy”, funded by the Intramural Research Program of Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 2010-2015. (My role: Co-investigator; PI: Cuilin Zhang)

  3. “Alpha-linolenic acid improves age-related memory function through CREB activation mediated pathways”, funded by National Natural Science Foundation of China (NSFC-31171681), 2012-2015. (My role: Co-investigator; PI: Jiqu Xu)

  4. “Alcohol-induced iron overload and LIP disorders and the antagonistic effects by quercetin”, funded by National Natural Science Foundation of China (NSFC-81172658), 2012-2015. (My role: Co-investigator; PI: Ping Yao)

  5. “The risk identification and intervention strategies for susceptibility to mother to child transmission of HBV infection”, funded by National Natural Science Foundation of China (NSFC-81172678), 2012-2015. (My role: Co-investigator; PI: Yukai Du)

  6. “Role of HO/CO-mediated signaling pathways in the protective effects of lotus seedpod procyanidins on age-related memory/cognition impairment”, funded by National Natural Science Foundation of China (NSFC-81072291), 2011-2013. (My role: Co-investigator; PI: Liegang Liu)

Completed Research Programs

  1. “Plasma HO-1 levels, ferritin, and HO-1 gene polymorphisms in individuals with type 2 diabetes mellitus”, funded by the Doctoral Innovation Fund of Huazhong University of Science & Technology, 2010-2011. (My role: PI)

  2. “Application of novel curcumin nanoparticles in protecting against ethanol-induced liver damage”, funded by the Graduates' Innovation Fund of Huazhong University of Science & Technology, 2010-2011. (My role: PI)

  3. “Synergic effect of curcumin and zinc-enriched yeast in protecting against ethanol-induced liver damage”, funded by the Graduates' Innovation Fund of Huazhong University of Science & Technology, 2009-2010. (My role: PI)

  4. “Whole-genome association and pharmacogenomics studies in type 2 diabetes mellitus”, funded by National High Technology Research and Development Program of China (863 Program, 2009AA022704), 2009-2010. (My role: Co-investigator; PI: Xu Lin)

  5. “Curcumin, a natural antioxidant, may attenuate type 2 diabetes mellitus via Nrf2/HO-1 mediated molecular pathway”, funded by National Natural Science Foundation of China (NSFC-30872116), 2009-2011. (My role: Co-investigator; PI: Liegang Liu)

  6. “Diet and lifestyle intervention in postpartum women in China”, funded by National Key Technology R&D Program of China (2008BAI58B07), 2008-2010. (My role: Co-investigator; PI: Liegang Liu)

PEER-REVIEWED PUBLICATIONS

  1. Bao W, Rong S, Zhang M, Yu X, Zhao Y, Xiao X, Yang W, Wang D, Yao P, Hu FB, Liu L. Plasma heme oxygenase-1 concentration in relation to impaired glucose regulation in a non-diabetic Chinese population. PLoS One. 2012;7(3):e32223.

  2. Bao W, Song F, Li X, Rong S, Yang W, Zhang M, Yao P, Hao L, Yang N, Hu FB, Liu L. Plasma heme oxygenase-1 concentration is elevated in individuals with type 2 diabetes mellitus. PLoS One. 2010, 5(8): e12371.

  3. Bao W, Song F, Li X, Rong S, Yang W, Wang D, Xu J, Fu J, Zhao Y, Liu L. Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes mellitus: a HuGE review and meta-analysis. Am J Epidemiol. 2010;172(6):631-6.

  4. Bao W, Li K, Rong S, Yao P, Hao L, Ying C, Zhang X, Nussler A, Liu L. Curcumin alleviates ethanol-induced hepatocytes oxidative damage involving heme oxygenase-1 induction. J Ethnopharmacol. 2010;128(2):549-53.

  5. Bao W, Ma AG, Mao LM, Lai JQ, Xiao M, Sun G, Ouyang YY, Wu S, Yang W, Wang NP, Zhao YT, Fu J, Liu LG. Diet and lifestyle interventions in postpartum women in china: study design and rationale of a multicenter randomized controlled trial. BMC Public Health. 2010;10:103.

  6. Rong Y, Bao W (Co-first-author), Rong S, Fang M, Wang D, Yao P, Hu FB, and Liu L. Hemochromatosis Gene (HFE) Polymorphisms and Risk of Type 2 Diabetes Mellitus: a Meta-Analysis. Am J Epidemiol. 2012. (In press).

  7. Li H, Gan W, Lu L, Dong X, Han X, Hu C, Yang Z, Sun L, Bao W, Li P, He M, Sun L, Wang Y, Zhu J, Ning Q, Tang Y, Zhang R, Wen J, Wang D, Zhu X, Guo K, Zuo X, Guo X, Yang H, Zhou X, DIAGRAM Consortium, AGEN-T2D Consortium, Zhang X, Qi L, Loos R, Hu F, Wu T, Liu Y, Liu L, Yang Z, Hu R, Jia W, Ji L, Li Y, and Lin X. A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans. Diabetes. 2012. (In press).

  8. Li H, Kilpeläinen TO, Liu C, Zhu J, Liu Y, Hu C, Yang Z, Zhang W, Bao W, Cha S, Wu Y, Yang T, Sekine A, Choi BY, Yajnik CS, Zhou D, Takeuchi F, Yamamoto K, Chan JC, Mani KR, Been LF, Imamura M, Nakashima E, Lee N, Fujisawa T, Karasawa S, Wen W, Joglekar CV, Lu W, Chang Y, Xiang Y, Gao Y, Liu S, Song Y, Kwak SH, Shin HD, Park KS, Fall CH, Kim JY, Sham PC, Lam KS, Zheng W, Shu X, Deng H, Ikegami H, Krishnaveni GV, Sanghera DK, Chuang L, Liu L, Hu R, Kim Y, Daimon M, Hotta K, Jia W, Kooner JS, Chambers JC, Chandak GR, Ma RC, Maeda S, Dorajoo R, Yokota M, Takayanagi R, Kato N, Lin X, Loos RJ. Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia. 2012;55(4):981-95.

  9. Rong S, Zhao Y, Bao W, Xiao X, Wang D, Nussler AK, Yan H, Yao P, Liu L. Curcumin prevents chronic alcohol-induced liver disease involving decreasing ROS generation and enhancing antioxidative capacity. Phytomedicine. 2012;19(6):545-50.

  10. Liu J, Bao W, Jiang M, Zhang Y, Zhang X, Liu L. Chromium, selenium, and zinc multimineral enriched yeast supplementation ameliorates diabetes symptom in streptozocin-induced mice. Biol Trace Elem Res. 2012;146(2):236-45.

  11. Xu J, Rong S, Xie B, Sun Z, Deng Q, Bao W, Wang D, Yao P, Huang F, Liu L. Changes in the nitric oxide system contribute to effect of procyanidins extracted from the lotus seedpod ameliorating memory impairment in cognitively impaired aged rats. Rejuvenation Res. 2011;14(1):33-43.

  12. Wang D, Xu K, Zhong Y, Luo X, Xiao R, Hou Y, Bao W, Yang W, Yan H, Yao P, Liu L. Acute and subchronic oral toxicities of Pu-erh black tea extract in Sprague-Dawley rats. J Ethnopharmacol. 2011;134(1):156-64.

  13. Wang D, Zhong Y, Luo X, Wu S, Xiao R, Bao W, Yang W, Yan H, Yao P, Liu L. Pu-erh black tea supplementation decreases quinocetone-induced ROS generation and oxidative DNA damage in Balb/c mice. Food Chem Toxicol. 2011;49(2):477-84.

  14. Shu XO, Long J, Cai Q, Qi L, Xiang YB, Cho YS, Tai ES, Li X, Lin X, Chow WH, Go MJ, Seielstad M, Bao W, Li H, Cornelis MC, Yu K, Wen W, Shi J, Han BG, Sim XL, Liu L, Qi Q, Kim HL, Ng DP, Lee JY, Kim YJ, Li C, Gao YT, Zheng W, Hu FB. Identification of new genetic risk variants for type 2 diabetes. PLoS Genet. 2010;6(9): e1001127.

  15. Xu J, Rong S, Xie B, Sun Z, Deng Q, Wu H, Bao W, Wang D, Yao P, Huang F, Liu L. Memory impairment in cognitively impaired aged rats associated with decreased hippocampal CREB phosphorylation: reversal by procyanidins extracted from the lotus seedpod. J Gerontol A Biol Sci Med Sci. 2010;65(9):933-40.

  16. Li X, Song F, Jiang H, Zhang M, Lin J, Bao W, Yao P, Yang X, Hao L, Liu L. A genetic variation in the fat mass- and obesity-associated gene is associated with obesity and newly diagnosed type 2 diabetes in a Chinese population. Diabetes Metab Res Rev. 2010;26(2):128-32.

  17. Wu H, Xu J, Zhuo L, Han L, Bao W, Rong S, Yao P, Ying C, Liu L. Comparison of risk factors associated with hypertension subtypes by classification tree method in Tongshan County of Jiangsu Province, China. Am J Hypertens. 2009;22(12):1287-94.

PRESENTATIONS IN INTERNATIONAL CONFERENCES

Oral presentation

  1. Bao W, Bowers K, Tobias DK, Hu FB, Zhang C. Pre-pregnancy nut and peanut butter consumption and the risk of gestational diabetes mellitus. The 45th Annual Meeting of the Society for Epidemiologic Research (SER), June 27-30, 2012, Minneapolis, Minnesota, USA.

  2. Bao W, Rong S, Rong Y, Yu X, Hu FB, Liu L. Predicting risk of type 2 diabetes mellitus with genome-wide association markers: a systematic review and meta-analysis. The International Diabetes Federation’s 21th World Diabetes Congress, December 4-8, 2011. Dubai, United Arab Emirates.

  3. Bao W, Rong S, Zhang M, Yu X, Zhao Y, Xiao X, Yang W, Wang D, Hu FB, Liu L. Elevated plasma heme oxygenase-1 concentration is associated with prediabetes in a Chinese population. The International Diabetes Federation’s 21th World Diabetes Congress, December 4-8, 2011, Dubai, United Arab Emirates.

  4. Bao W, Li K, Liu S, Zhang BY, Li N, Wang D, Yao P, Nussler AK, Liu LG. Curcumin Exerts Hepatoprotective Effects against Ethanol-induced Oxidative Damage through an Emerging Signal Pathway: Involvement of Heme Oxygenase-1 Induction. Hepatol Int. 2009; 3(3):40. The 19th Conference of the Asian Pacific Association for the Study of the Liver (APASL), Feb 13-16, 2009, Hong Kong, China.

  5. Bao W, Li K, Liu S, Zhang BY, Zhou SL, Yao P, Liu LG. Curcumin, a dietary natural phytochemical, ameliorates ethanol-induced cell injuries in rat primary hepatocytes via antioxidative approach. Hepatol Int. 2008; 2(S2):55. The 4th Hong Kong-Shanghai International Liver Congress, June 12-15, 2008, Hong Kong, China.

Poster presentation

  1. Bao W, Bowers K, Kiely M, Yeung E, Zhang C. Genetic variants of gestational diabetes: what are in common with type 2 diabetes? The 25th Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research (SPER), June 25-27, 2012, Minneapolis, Minnesota, USA.

  2. Bao W, Bowers K, Tobias DK, Hu FB, Zhang C. Pre-pregnancy nut and peanut butter consumption and the risk of gestational diabetes mellitus. The 25th Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research (SPER), June 25-27, 2012, Minneapolis, Minnesota, USA.

  3. Bao W, Song F, Rong S, Yang W, Zhao Y, Yao P, Liu L. Relationships among Heme Oxygenase-1 Gene Microsatellite Polymorphism, Body Iron Stores and Type 2 Diabetes in a Chinese Population. The 8th International Diabetes Federation Western Pacific Region Congress, October 17-20, 2010, Busan, Korea.

  4. Bao W, Song F, Li X, Rong S, Yang W, Hu F, Liu L. Association between Heme Oxygenase-1 Gene Microsatellite Polymorphisms and Type 2 Diabetes: A Systematic Review and Meta-Analysis. The American Diabetes Association’s 70th Scientific Sessions, June 25-29, 2010, Orlando, Florida, USA.

  5. Bao W, Song F, Li X, Rong S, Yang W, Zhang M, Yao P, Hao L, Yang N, Hu F, Liu L. Elevated Plasma Heme Oxygenase-1 Concentrations Are Associated with Higher Risk of Type 2 Diabetes Mellitus in a Chinese Population. The American Diabetes Association’s 70th Scientific Sessions, June 25-29, 2010, Orlando, Florida, USA.

  6. Bao W, Rong S, Yang W, Yao P, Nussler A, Liu L. Transforming Growth Factor-beta (TGF-beta) Gene Polymorphisms and Susceptibility of Alcoholic Liver Disease: A Meta-Analysis. Hepatol Int. 2010; 4(1):223. The 20th Conference of the Asian Pacific Association for the Study of the Liver (APASL), March 25-28, 2010, Beijing, China.

  7. Bao W, Jiang M, Rong S, Song F, Yao P, Nussler A, Liu L. Multiminerals-enriched Yeast Alleviates Oxidative Stress, Metabolic Disorders and Immune Function Impairment in Streptozocin-induced Diabetic Mice. The International Diabetes Federation’s 20th World Diabetes Congress, October 18-22, 2009, Montreal, Canada.